Biomechanical characterization of a low density silicone elastomer filled with hollow microspheres for maxillofacial prostheses
文献类型：期刊论文
| 作者 | Liu, Q.1; Shao, L. Q.1; Xiang, H. F.2; Zhen, D.2; Zhao, N.2; Yang, S. G.3; Zhang, X. L.2; Xu, J.2 |
| 刊名 | JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
 |
| 出版日期 | 2013-08-01 |
| 卷号 | 24期号:11页码:1378-1390 |
| 关键词 | Maxillofacial Prosthesis Silicone Elastomer Hollow Microspheres |
| ISSN号 | 0920-5063 |
| DOI | 10.1080/09205063.2012.762292 |
| 英文摘要 | An ideal material for maxillofacial prostheses has not been found. We created a novel material: silicone elastomer filled with hollow microspheres and characterized its biomechanical properties. Expancel hollow microspheres were mixed with MDX4-4210 silicone elastomer using Q7-9180 silicone fluid as diluent. The volume fractions of microspheres were 0, 5, 15, and 30%v/v (volume ratio to the total volume of MDX4-4210 and microspheres). The microspheres dispersed well in the matrix. The physical properties and biocompatibility of the composites were examined. Shock absorption was the greatest by the 5%v/v composite, and decreased with increasing concentrations of microspheres. The density, thermal conductivity, Shore A hardness, tear and tensile strength decreased with increasing concentrations of microspheres, while elongation at break increased. Importantly, the tear strength of all composites was markedly lower than that of pure silicone elastomer. Cell viability assays indicated that the composite was of good biocompatibility. The composite with a volume fraction of 5% exhibited the optimal properties for use as a maxillofacial prosthesis, though its tear strength was markedly lower than that of silicone elastomer. In conclusion, we developed a novel light and soft material with good flexibility and biocompatibility, which holds a promising prospect for clinical application as maxillofacial prosthesis. |
| 语种 | 英语 |
| WOS记录号 | WOS:000320753600008 |
| 出版者 | TAYLOR & FRANCIS LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/42153]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Shao, L. Q. |
| 作者单位 | 1.Southern Med Univ, Nanfang Hosp, Sch Stomatol, Guangzhou, Guangdong, Peoples R China 2.Chinese Acad Sci, Inst Chem, Lab Polymer Phys & Chem, Beijing Natl Lab Mol Sci, Beijing 100080, Peoples R China 3.Donghua Univ, Coll Mat Sci & Engn, State Key Lab Modificat Chem Fibers & Polymer Mat, Shanghai, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Q.,Shao, L. Q.,Xiang, H. F.,et al. Biomechanical characterization of a low density silicone elastomer filled with hollow microspheres for maxillofacial prostheses[J]. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION,2013,24(11):1378-1390. |
| APA | Liu, Q..,Shao, L. Q..,Xiang, H. F..,Zhen, D..,Zhao, N..,...&Xu, J..(2013).Biomechanical characterization of a low density silicone elastomer filled with hollow microspheres for maxillofacial prostheses.JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION,24(11),1378-1390. |
| MLA | Liu, Q.,et al."Biomechanical characterization of a low density silicone elastomer filled with hollow microspheres for maxillofacial prostheses".JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION 24.11(2013):1378-1390. |
入库方式： OAI收割
来源：化学研究所
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