Visually multiplexed quantitation of heavy metal ions in water using volumetric bar-chart chip
文献类型：期刊论文
| 作者 | Liu, Xinli1; Wang, Yuzhen2,3,4; Song, Yujun1 |
| 刊名 | BIOSENSORS & BIOELECTRONICS
 |
| 出版日期 | 2018-10-15 |
| 卷号 | 117页码:644-650 |
| 关键词 | Microfluidics Heavy Metal Ions Biosensor Platinum Nanoparticles |
| ISSN号 | 0956-5663 |
| DOI | 10.1016/j.bios.2018.06.046 |
| 英文摘要 | Heavy metal ions monitoring in water is practically significant for the environment and the human health. In this work, a lab-on-a-chip biosensor was developed for multiplexed quantitation of heavy metal ions by the integration of triple-channel volumetric bar-chart chip with DNA-nanoparticle probes. This method possesses the capability for rapid detection of Cu2+, Pb2+ and Hg2+ simultaneously with high sensitivity, selectivity and accuracy. Due to the highly catalase-like activity of the urchin-like platinum nanoparticles, this sensor exhibits high sensitivity with the detection limits of 1.0 nM, 1.0 nM and 1.8 nM for sensing of Cu2+, Pb2+ and Hg2+ respectively, which are much lower than the requirement of the United States Environmental Protection Agency (EPA) in drink water and superior to the colorimetric method based on the metal ion-specific DNA assay. The accuracy and reliability were verified by our Atomic Absorption Spectrometry (AAS) and Atomic Fluorescence Spectroscopy (AFS) measurements of real water sample. As the results can be directly read out without the need of the external instruments or complicate data processing, this sensor is extremely practical for environmental applications. |
| 语种 | 英语 |
| WOS记录号 | WOS:000442191900080 |
| 出版者 | ELSEVIER ADVANCED TECHNOLOGY |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/42429]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wang, Yuzhen; Song, Yujun |
| 作者单位 | 1.Nanjing Univ, Dept Biomed Engn, Coll Engn & Appl Sci, Nanjing 210093, Jiangsu, Peoples R China 2.Nanjing Tech Univ NanjingTech, Jiangsu Natl Synergist Innovat Ctr Adv Mat SICAM, Key Lab Flexible Elect, Nanjing 211816, Jiangsu, Peoples R China 3.Nanjing Tech Univ NanjingTech, Jiangsu Natl Synergist Innovat Ctr Adv Mat SICAM, Inst Adv Mat, Nanjing 211816, Jiangsu, Peoples R China 4.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Jilin, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Xinli,Wang, Yuzhen,Song, Yujun. Visually multiplexed quantitation of heavy metal ions in water using volumetric bar-chart chip[J]. BIOSENSORS & BIOELECTRONICS,2018,117:644-650. |
| APA | Liu, Xinli,Wang, Yuzhen,&Song, Yujun.(2018).Visually multiplexed quantitation of heavy metal ions in water using volumetric bar-chart chip.BIOSENSORS & BIOELECTRONICS,117,644-650. |
| MLA | Liu, Xinli,et al."Visually multiplexed quantitation of heavy metal ions in water using volumetric bar-chart chip".BIOSENSORS & BIOELECTRONICS 117(2018):644-650. |
入库方式： OAI收割
来源：化学研究所
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