Controlled movement of kinesin-driven microtubule along a directional track
文献类型：期刊论文
| 作者 | Xia, Jiarui1,2; Sun, Bingbing1,3; Yang, Yang2; Li, Jieling1; Jia, Yi1; Dong, Weiguang1; Li, Junbai1,3 |
| 刊名 | COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
 |
| 出版日期 | 2018-08-05 |
| 卷号 | 550页码:186-192 |
| 关键词 | Surface Modification Kinesin Microtubule Controlled Movement Nanodevice |
| ISSN号 | 0927-7757 |
| DOI | 10.1016/j.colsurfa.2018.04.049 |
| 英文摘要 | We designed a system for the controlled directional movements of kinesin-driven microtubule by restricting the motor coating areas in a two-dimensional (2D) substrate. The t-butoxycarbonyl (Boc) was firstly introduced in an amine groups modified glass surface to construct 2D track. The polarity of the above mentioned glass can be efficiently reversed after Boc protection, resulting in the surface transferring from hydrophilicity to hydrophobicity. Through a selective treatment of Boc de-protection, the substrate surface can be distributed into hydrophilic and hydrophobic partitions. The hydrophilic areas can be observed by labeling nanoparticles or fluorescent dye, thus the different shapes were formed at the substrate. The hydrophilic parts in the substrates will allow kinesin to be selectively immobilized on this surface and result in the controlled directional movement of microtubule. With this design, the selective decoration of 2D tracks may have a potential application in field of biomolecular motors based nanodevice. |
| 语种 | 英语 |
| WOS记录号 | WOS:000432552600022 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/42803]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Jia, Yi; Li, Junbai |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, BNLMS, CAS Key Lab Colloid Interface & Chem Thermodynam, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xia, Jiarui,Sun, Bingbing,Yang, Yang,et al. Controlled movement of kinesin-driven microtubule along a directional track[J]. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,2018,550:186-192. |
| APA | Xia, Jiarui.,Sun, Bingbing.,Yang, Yang.,Li, Jieling.,Jia, Yi.,...&Li, Junbai.(2018).Controlled movement of kinesin-driven microtubule along a directional track.COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,550,186-192. |
| MLA | Xia, Jiarui,et al."Controlled movement of kinesin-driven microtubule along a directional track".COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 550(2018):186-192. |
入库方式： OAI收割
来源：化学研究所
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