Studies of gold nanorod-iron oxide nanohybrids for immunoassay based on SPR biosensor
文献类型：期刊论文
| 作者 | Zhang, Hua1; Sun, Ying1; Gao, Shang1; Zhang, Hanqi1; Zhang, Jia1; Bai, Yu2; Song, Daqian1 |
| 刊名 | TALANTA
 |
| 出版日期 | 2014-07-01 |
| 卷号 | 125页码:29-35 |
| 关键词 | Surface Plasmon Resonance (Spr) Gnr-fe3o4 Nanohybrids Biosensor Mouse Igg |
| ISSN号 | 0039-9140 |
| DOI | 10.1016/j.talanta.2014.02.036 |
| 英文摘要 | A wavelength modulation surface plasmon resonance (SPR) biosensor based on gold nanorods-Fe3O4 (GNR-Fe3O4) nanohybrids was developed for the determination of mouse IgG. The premade negatively charged Fe3O4 nanoparticles were coated on the surface of positively charged GNRs through electrostatic interaction. The synthetic method was simple, quick and easy operation. The aldehyde group functionalized GNR-Fe3O4 nanohybrids possess unique magnetic property, exceptional optical property and good biocompatibility, which can be used as immobilization matrix for biomolecules. The magnetic nanohybrids can be easily immobilized on the surface of SPR biosensor chip with a magnetic pillar, which simplifies the experimental procedure. The effects of GNR-Fe3O4 nanohybrids on the sensitivity of SPR biosensor were also studied. The SPR biosensor based on GNR-Fe3O4 nanohybrids shows a good response to mouse IgG in the concentration range of 0.15-40.00 mu g mL(-1), while the biosensor based on MPA and Fe3O4 nanoparticles show a good response to mouse IgG in the concentration range of 2.50-40.00 mu g mL(-1) and 1.25-40.00 mu g mL(-1), respectively. As a result, when GNR-Fe3O4 nanohybrids were used in SPR biosensor, the sensitivity for the determination of mouse IgG is significantly enhanced. (C) 2014 Elsevier B.V. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000336872200005 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/43527]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Song, Daqian |
| 作者单位 | 1.Jilin Univ, Coll Chem, Changchun 130012, Peoples R China 2.Peking Univ, Coll Chem & Mol Engn, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Hua,Sun, Ying,Gao, Shang,et al. Studies of gold nanorod-iron oxide nanohybrids for immunoassay based on SPR biosensor[J]. TALANTA,2014,125:29-35. |
| APA | Zhang, Hua.,Sun, Ying.,Gao, Shang.,Zhang, Hanqi.,Zhang, Jia.,...&Song, Daqian.(2014).Studies of gold nanorod-iron oxide nanohybrids for immunoassay based on SPR biosensor.TALANTA,125,29-35. |
| MLA | Zhang, Hua,et al."Studies of gold nanorod-iron oxide nanohybrids for immunoassay based on SPR biosensor".TALANTA 125(2014):29-35. |
入库方式： OAI收割
来源：化学研究所
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