Complexation of DNA with cationic surfactants as studied by small-angle X-ray scattering
文献类型：期刊论文
| 作者 | Niu Lin1,2; Yan JingJing1,2; Yang XuYan1,2; Burger, Christian3; Rong LiXia3; Hsiao, Benjamin3; Liang DeHai1,2 |
| 刊名 | SCIENCE CHINA-CHEMISTRY
 |
| 出版日期 | 2014-12-01 |
| 卷号 | 57期号:12页码:1738-1745 |
| 关键词 | Phase Behavior Dna Surfactant Synchrotron Small-angle X-ray Scattering Kinetics |
| ISSN号 | 1674-7291 |
| DOI | 10.1007/s11426-014-5159-y |
| 英文摘要 | The phase behaviors of the complex formed by didodecyldimethylammonium bromide (DDAB) and cetyltrimethylammonium bromide (CTAB) interacting with three different types of DNAs, salmon testes DNA (similar to 2000 bp), 21-bp double-stranded oligonucleotides (oligo-dsDNA), and 21-nt single-stranded oligonucleotides (oligo-ssDNA) were studied by synchrotron small-angle X-ray scattering. It was found that the DNA length and flexibility, together with the positive/negative charge ratio, determined the final structure. At higher charge ratios, the DNA length exhibited negligible effect. Both oligo-dsDNA and salmon DNA formed inverted hexagonal packing of cylinders with CTAB, as well as bilayered lamella with DDAB. However, at lower charge ratios, oligo-dsDNA formed a distorted hexagonal phase with CTAB and a new structure with DDAB, which was different from the behaviors of salmon DNA. The flexible oligo-ssDNA formed rich structures that were subject to environmental disturbance. Kinetic study also indicated that the structures of the complex formed by oligo-ssDNA took much longer to mature than the structures formed by oligo-dsDNA. We attributed this result to the conformational adjustment of oligo-ssDNA in the complex. |
| 语种 | 英语 |
| WOS记录号 | WOS:000346047500017 |
| 出版者 | SCIENCE PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/43535]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Liang DeHai |
| 作者单位 | 1.Peking Univ, Minist Educ, Key Lab Polymer Chem & Phys, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China 2.Peking Univ, Coll Chem & Mol Engn, Dept Polymer Sci & Engn, Beijing 100871, Peoples R China 3.SUNY Stony Brook, Dept Chem, Stony Brook, NY 11794 USA |
| 推荐引用方式 GB/T 7714 | Niu Lin,Yan JingJing,Yang XuYan,et al. Complexation of DNA with cationic surfactants as studied by small-angle X-ray scattering[J]. SCIENCE CHINA-CHEMISTRY,2014,57(12):1738-1745. |
| APA | Niu Lin.,Yan JingJing.,Yang XuYan.,Burger, Christian.,Rong LiXia.,...&Liang DeHai.(2014).Complexation of DNA with cationic surfactants as studied by small-angle X-ray scattering.SCIENCE CHINA-CHEMISTRY,57(12),1738-1745. |
| MLA | Niu Lin,et al."Complexation of DNA with cationic surfactants as studied by small-angle X-ray scattering".SCIENCE CHINA-CHEMISTRY 57.12(2014):1738-1745. |
入库方式： OAI收割
来源：化学研究所
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