A NOVEL REAGENT, DIALKYLPHOSPHITE, FOR PEPTIDE-SYNTHESIS
文献类型：期刊论文
| 作者 | ZHAO, YF; ZHANG, DQ; XUE, CB |
| 刊名 | INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH
 |
| 出版日期 | 1991-05-01 |
| 卷号 | 37期号:5页码:457-461 |
| 关键词 | Activated Amide C-13-nmr N-dipp-amino Acid N-dipp-dipeptide Acids N-dipp-tripeptide Esters Fab-ms P-31-nmr |
| ISSN号 | 0367-8377 |
| 英文摘要 | The same dialkylphosphite reagent can be used for both N protection and C activation of amino acids. Two N-diisopropyloxyphosphinyl (Dipp) tripeptide esters were prepared, and nine N-Dipp-dipeptide acids were synthesized through the activated amide intermediate. The positive ion FAB-MS of N-Dipp-tripeptide showed novel cleavage patterns in that only the N-phosphoryl fragment ions gave intense peaks while the C-terminal series ions did not appear. This novel character might be useful for peptide sequence analysis. In addition, dialkyloxyphosphinyl group can be examined by P-31-NMR for peptide conformational analysis and inspection for the degree of racemization during the coupling reaction. |
| 语种 | 英语 |
| WOS记录号 | WOS:A1991FN06300012 |
| 出版者 | MUNKSGAARD INT PUBL LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/44157]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | ZHAO, YF |
| 作者单位 | CHINESE ACAD SCI,INST CHEM,BEIJING,PEOPLES R CHINA |
| 推荐引用方式 GB/T 7714 | ZHAO, YF,ZHANG, DQ,XUE, CB. A NOVEL REAGENT, DIALKYLPHOSPHITE, FOR PEPTIDE-SYNTHESIS[J]. INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH,1991,37(5):457-461. |
| APA | ZHAO, YF,ZHANG, DQ,&XUE, CB.(1991).A NOVEL REAGENT, DIALKYLPHOSPHITE, FOR PEPTIDE-SYNTHESIS.INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH,37(5),457-461. |
| MLA | ZHAO, YF,et al."A NOVEL REAGENT, DIALKYLPHOSPHITE, FOR PEPTIDE-SYNTHESIS".INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH 37.5(1991):457-461. |
入库方式： OAI收割
来源：化学研究所
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