Effect of loop on the stability of intramolecular triplex DNA
文献类型：期刊论文
| 作者 | Yang, LJ; Bai, CL; Lee, IS; Wang, XW; Wang, C |
| 刊名 | SCIENCE IN CHINA SERIES B-CHEMISTRY
 |
| 出版日期 | 1997-12-01 |
| 卷号 | 40期号:6页码:650-656 |
| 关键词 | Loop Intra-triplex Dna Stability Molecular Mechanics |
| ISSN号 | 1001-652X |
| 英文摘要 | Conformation stabilities of intramolecular triple-helical DNAs (intra-triplex DNAs: 5'-d(TC)(6)-d(T)(m)-d(CT)(6)-d(C)(n)-d(AG)(6)-3', where m and n are chosen to be 4 and 3) have been examined by molecular mechanics. The four inta-triplexes (H-DNAs) are compared with the intermolecular triplexes d(TC)(6) * d(AG)(6)-d(CT)(6). The results revealed that loops do not significantly influence the intratriplex conformations, loop conformations, however, depend partly on its length. Loop also makes strand II of every intra-triplex DNA longer than that of the inter-tripler DNA. Most of residue sugar conformations of triple-helical DNAs are S-type, there also exist, however, N-type conformation and the conformations between S-type and N-type. Possible models of the five tripler DNAs are presented. |
| 语种 | 英语 |
| WOS记录号 | WOS:A1997YK88500012 |
| 出版者 | SCIENCE CHINA PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/44721]  |
| 专题 | 中国科学院化学研究所 |
| 作者单位 | CHINESE ACAD SCI,INST CHEM,BEIJING 100080,PEOPLES R CHINA |
| 推荐引用方式 GB/T 7714 | Yang, LJ,Bai, CL,Lee, IS,et al. Effect of loop on the stability of intramolecular triplex DNA[J]. SCIENCE IN CHINA SERIES B-CHEMISTRY,1997,40(6):650-656. |
| APA | Yang, LJ,Bai, CL,Lee, IS,Wang, XW,&Wang, C.(1997).Effect of loop on the stability of intramolecular triplex DNA.SCIENCE IN CHINA SERIES B-CHEMISTRY,40(6),650-656. |
| MLA | Yang, LJ,et al."Effect of loop on the stability of intramolecular triplex DNA".SCIENCE IN CHINA SERIES B-CHEMISTRY 40.6(1997):650-656. |
入库方式： OAI收割
来源：化学研究所
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