Palladium-Catalyzed Regioselective Oxidative Annulation of Cyclohexanones and 2-Aminophenyl Ketones Using Molecular Oxygen as the Sole Oxidant
文献类型：期刊论文
| 作者 | Mu, Wan-Lu1; Wang, Meirong2; Li, Hui-Jing1; Huang, Deng-Ming1; Zhang, Yi-Yun1; Li, Chao-Yi1; Liu, Ying1; Wu, Yan-Chao1,3 |
| 刊名 | ADVANCED SYNTHESIS & CATALYSIS
 |
| 出版日期 | 2017-12-11 |
| 卷号 | 359期号:23页码:4250-4257 |
| 关键词 | Palladium-catalyzed Aerobic Oxidation Synthesis Acridines Regioselective |
| ISSN号 | 1615-4150 |
| DOI | 10.1002/adsc.201700715 |
| 英文摘要 | A facile oxidative annulation of cyclohexanones and 2-aminophenyl ketones that uses molecular oxygen as the sole oxidant is described. The reaction provides a direct approach to acridines, a structural motif for a large number of fluorescent sensors, functional materials, ligands, and pharmaceuticals. In the presence of a palladium catalyst, high regioselectivity is observed when using non-symmetric 3-substituted cyclohexanones. With the use of oxygen as the terminal redox moderator, the electron gap of the global redox condensation process is filled and the reaction efficiency is significantly promoted. This protocol possesses many advantages such as using nonhazardous oxidant and readily available starting materials, high regioselectivity, and water as the only by-product. |
| 语种 | 英语 |
| WOS记录号 | WOS:000417648400024 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/45235]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Li, Hui-Jing; Wu, Yan-Chao |
| 作者单位 | 1.Harbin Inst Technol, Sch Marine Sci & Technol, Weihai 264209, Peoples R China 2.Harbin Inst Technol, Sch Mat Sci & Engn, Weihai 264209, Peoples R China 3.Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Mu, Wan-Lu,Wang, Meirong,Li, Hui-Jing,et al. Palladium-Catalyzed Regioselective Oxidative Annulation of Cyclohexanones and 2-Aminophenyl Ketones Using Molecular Oxygen as the Sole Oxidant[J]. ADVANCED SYNTHESIS & CATALYSIS,2017,359(23):4250-4257. |
| APA | Mu, Wan-Lu.,Wang, Meirong.,Li, Hui-Jing.,Huang, Deng-Ming.,Zhang, Yi-Yun.,...&Wu, Yan-Chao.(2017).Palladium-Catalyzed Regioselective Oxidative Annulation of Cyclohexanones and 2-Aminophenyl Ketones Using Molecular Oxygen as the Sole Oxidant.ADVANCED SYNTHESIS & CATALYSIS,359(23),4250-4257. |
| MLA | Mu, Wan-Lu,et al."Palladium-Catalyzed Regioselective Oxidative Annulation of Cyclohexanones and 2-Aminophenyl Ketones Using Molecular Oxygen as the Sole Oxidant".ADVANCED SYNTHESIS & CATALYSIS 359.23(2017):4250-4257. |
入库方式： OAI收割
来源：化学研究所
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