中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Revealing membrane permeability of polymersomes through fluorescence enhancement

文献类型:期刊论文

作者Quan, Li1; Ding, Hongyan1; Pan, Changjiang1; Wei, Yanchun1; Xie, Zhigang2
刊名COLLOIDS AND SURFACES B-BIOINTERFACES
出版日期2018
卷号161页码:156-161
关键词Fluorescence Polymersomes Permeability Bodipy
ISSN号0927-7765
DOI10.1016/j.colsurfb.2017.10.058
英文摘要In this work, permeability of polymersomes was quantified by fluorescence enhancement. The polymersomes were prepared from poly(ethylene glycol)-b-poly(epsilon-caprolactone)(PEG-PCL), and an acid sensitive hydrophobic dye borondipyrromethene (BODIPY) was encapsulated into the membrane of polymersomes. H+ from trifluoroacetic acid (TFA) would diffuse into the membrane of polymersomes to enhance the fluorescence of BODIPY. Intensity of the enhanced fluorescence could be used for quantifying the H+ permeability of polymersomes. In addition, poly(epsilon-caprolactone) (PCL) was used to control the permeability ability of the membrane. Such quantitative information on the molecular diffusion of polymersomes is of fundamental importance to many of their potential applications, e.g., nanoreactors and drug delivery. (C) 2017 Elsevier B.V. All rights reserved.
语种英语
WOS记录号WOS:000423636100019
出版者ELSEVIER SCIENCE BV
源URL[http://ir.iccas.ac.cn/handle/121111/45505]  
专题中国科学院化学研究所
通讯作者Pan, Changjiang; Xie, Zhigang
作者单位1.Huaiyin Inst Technol, Jiangsu Prov Key Lab Intervent Med Device, Huaian 223003, Jiangsu, Peoples R China
2.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Jilin, Peoples R China
推荐引用方式
GB/T 7714
Quan, Li,Ding, Hongyan,Pan, Changjiang,et al. Revealing membrane permeability of polymersomes through fluorescence enhancement[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2018,161:156-161.
APA Quan, Li,Ding, Hongyan,Pan, Changjiang,Wei, Yanchun,&Xie, Zhigang.(2018).Revealing membrane permeability of polymersomes through fluorescence enhancement.COLLOIDS AND SURFACES B-BIOINTERFACES,161,156-161.
MLA Quan, Li,et al."Revealing membrane permeability of polymersomes through fluorescence enhancement".COLLOIDS AND SURFACES B-BIOINTERFACES 161(2018):156-161.

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来源:化学研究所

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