Surface modification of polyisobutylene via grafting amino acid-based poly (acryloyl-6-aminocaproic acid) as multifunctional material
文献类型:期刊论文
作者 | Du, Yanqiu1,2; Li, Chunming1; Jin, Jing1; Li, Chao3; Jiang, Wei1 |
刊名 | COLLOIDS AND SURFACES B-BIOINTERFACES
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出版日期 | 2018 |
卷号 | 161页码:73-82 |
关键词 | Polyisobutylene Poly (Acryloyl-6-aminocaproic Acid) Hemocompatibility Concanavalin a Erythrocyte |
ISSN号 | 0927-7765 |
DOI | 10.1016/j.colsurfb.2017.10.035 |
英文摘要 | Amino acid-based P(acryloyl-6-aminocaproic acid) (PAACA) brushes were fabricated on polyisobutylene (PIB) surface combined with plasma pre-treatment and UV-induced grafting polymerization to construct an antifouling and functional material. The hydrophilicity and hemocompatibility of PIB were largely improved by surface modification of AACA, which were confirmed by water contact angle and platelet adhesion, respectively. PAACA brushes were precisely located onto the surface of PIB to create a patterned PIB-g-PAACA structure, and then the carboxyl groups on PAACA was activated to immobilize functional protein-Concanavalin A (Con A). The obtained Con A-coupled microdomains could further capture erythrocytes. This method developed a platform on commercial PIB surface via amino acid-based polymer brushes which had a promising application in drug delivery and disease diagnosis. (C) 2017 Elsevier B.V. All rights reserved. |
语种 | 英语 |
WOS记录号 | WOS:000423636100010 |
出版者 | ELSEVIER SCIENCE BV |
源URL | [http://ir.iccas.ac.cn/handle/121111/45543] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Jin, Jing; Jiang, Wei |
作者单位 | 1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Jilin, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Qingdao Univ, Dept Infect, Affiliated Hosp, Qingdao 266003, Peoples R China |
推荐引用方式 GB/T 7714 | Du, Yanqiu,Li, Chunming,Jin, Jing,et al. Surface modification of polyisobutylene via grafting amino acid-based poly (acryloyl-6-aminocaproic acid) as multifunctional material[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2018,161:73-82. |
APA | Du, Yanqiu,Li, Chunming,Jin, Jing,Li, Chao,&Jiang, Wei.(2018).Surface modification of polyisobutylene via grafting amino acid-based poly (acryloyl-6-aminocaproic acid) as multifunctional material.COLLOIDS AND SURFACES B-BIOINTERFACES,161,73-82. |
MLA | Du, Yanqiu,et al."Surface modification of polyisobutylene via grafting amino acid-based poly (acryloyl-6-aminocaproic acid) as multifunctional material".COLLOIDS AND SURFACES B-BIOINTERFACES 161(2018):73-82. |
入库方式: OAI收割
来源:化学研究所
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