Cu(I)-Catalyzed Asymmetric Cross-Coupling of N-Tosylhydrazones and Trialkylsilylethynes: Enantioselective Construction of C(sp)C(sp(3)) Bonds
文献类型：期刊论文
| 作者 | Chu, Wen-Dao1,2,3; Guo, Fangfang2,3; Yu, Lefei2,3; Hong, Junting2,3; Liu, Qianyi2,3; Mo, Fanyang2,3; Zhang, Yan2,3; Wang, Jianbo2,3 |
| 刊名 | CHINESE JOURNAL OF CHEMISTRY
 |
| 出版日期 | 2018-03-01 |
| 卷号 | 36期号:3页码:217-222 |
| 关键词 | c(Sp)c(Sp(3)) Cross-coupling Metal Carbene Asymmetric Catalysis Cu(i) Catalysts N-tosylhydrazones |
| ISSN号 | 1001-604X |
| DOI | 10.1002/cjoc.201700633 |
| 英文摘要 | The first catalytic enantioselective C(sp)?C(sp(3)) cross-coupling reaction between N-tosylhydrazones and trialkylsilylethynes in the presence of Cu(I) salts and chiral phosphoramidite ligands was developed. A series of synthetically interesting, functionalized alkynes were obtained with moderate to good enantioselectivities (up to 83% ee). Cu(II) carbene migratory insertion is proposed to be the enantio-determining step. |
| 语种 | 英语 |
| WOS记录号 | WOS:000424885000007 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/45569]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wang, Jianbo |
| 作者单位 | 1.China West Normal Univ, Coll Chem & Chem Engn, Chem Synth & Pollut Control Key Lab Sichuan Prov, Nanchong 637002, Sichuan, Peoples R China 2.Peking Univ, Coll Chem, BNLMS, Beijing 100871, Peoples R China 3.Peking Univ, Coll Chem, Key Lab Bioorgan Chem & Mol Engn, Minist Educ, Beijing 100871, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chu, Wen-Dao,Guo, Fangfang,Yu, Lefei,et al. Cu(I)-Catalyzed Asymmetric Cross-Coupling of N-Tosylhydrazones and Trialkylsilylethynes: Enantioselective Construction of C(sp)C(sp(3)) Bonds[J]. CHINESE JOURNAL OF CHEMISTRY,2018,36(3):217-222. |
| APA | Chu, Wen-Dao.,Guo, Fangfang.,Yu, Lefei.,Hong, Junting.,Liu, Qianyi.,...&Wang, Jianbo.(2018).Cu(I)-Catalyzed Asymmetric Cross-Coupling of N-Tosylhydrazones and Trialkylsilylethynes: Enantioselective Construction of C(sp)C(sp(3)) Bonds.CHINESE JOURNAL OF CHEMISTRY,36(3),217-222. |
| MLA | Chu, Wen-Dao,et al."Cu(I)-Catalyzed Asymmetric Cross-Coupling of N-Tosylhydrazones and Trialkylsilylethynes: Enantioselective Construction of C(sp)C(sp(3)) Bonds".CHINESE JOURNAL OF CHEMISTRY 36.3(2018):217-222. |
入库方式： OAI收割
来源：化学研究所
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