Selective biocompatibility and responsive imaging property of cationic conjugated polyelectrolyte to cancer cells
文献类型：期刊论文
| 作者 | Wang, Bing; Nie, Chenyao; Liu, Libing; Lv, Fengting; Wang, Shu |
| 刊名 | CHINESE CHEMICAL LETTERS
 |
| 出版日期 | 2017-10-01 |
| 卷号 | 28期号:10页码:1975-1978 |
| 关键词 | Imaging Cell Conjugated Polymers Fluorescence Enhancement Long-wavelength Emission Selective Biocompatibility |
| ISSN号 | 1001-8417 |
| DOI | 10.1016/j.cclet.2017.07.002 |
| 英文摘要 | Optical imaging, as an important molecular imaging modality, has emerged many attractions in studying the biological or molecular events both in cell level and living subject because of its high resolution and sensitivity, noninvasive manner and low cost. Herein, we bring novel insights into a water-soluble conjugated polyelectlyte by deeply studying its properties in cells. Poly(9, 9-bis (6'-N,N,N-trimethylammonium hexyl)fluorene phenylene) (PFP), a good biosensing material, was studied in this paper. The biocompatibility of PFP was investigated in different cells, and cell cycle analysis was carried out to explore the reasons of different biocompatibility of PFP to cells. After irradiation, fluorescence enhancement of blue emission and turn-on of long-wavelength emission of PFP in HepG2 cells was observed, which was first reported as far as we know. The differentiated biocompatibility of PFP and its particular imaging properties in cancer cells can help to guide the application of conjugated polymers in cells and provide a new dimension in designing sensitive and responsive imaging materials. (C) 2017 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000426222000012 |
| 出版者 | ELSEVIER SCIENCE INC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/45681]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Liu, Libing; Wang, Shu |
| 作者单位 | Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Bing,Nie, Chenyao,Liu, Libing,et al. Selective biocompatibility and responsive imaging property of cationic conjugated polyelectrolyte to cancer cells[J]. CHINESE CHEMICAL LETTERS,2017,28(10):1975-1978. |
| APA | Wang, Bing,Nie, Chenyao,Liu, Libing,Lv, Fengting,&Wang, Shu.(2017).Selective biocompatibility and responsive imaging property of cationic conjugated polyelectrolyte to cancer cells.CHINESE CHEMICAL LETTERS,28(10),1975-1978. |
| MLA | Wang, Bing,et al."Selective biocompatibility and responsive imaging property of cationic conjugated polyelectrolyte to cancer cells".CHINESE CHEMICAL LETTERS 28.10(2017):1975-1978. |
入库方式： OAI收割
来源：化学研究所
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