Palladium-Catalyzed Oxygenative Cross-Coupling of Ynamides and Benzyl Bromides by Carbene Migratory Insertion
文献类型：期刊论文
| 作者 | Gao, Yunpeng1,2; Wu, Guojiao1,2; Zhou, Qi1,2; Wang, Jianbo1,2,3 |
| 刊名 | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
 |
| 出版日期 | 2018-03-01 |
| 卷号 | 57期号:10页码:2716-2720 |
| 关键词 | Carbenes Cross-coupling Oxidation Palladium Ynamides |
| ISSN号 | 1433-7851 |
| DOI | 10.1002/anie.201712795 |
| 英文摘要 | A palladium-catalyzed oxygenative cross-coupling of ynamides and benzyl bromides has been developed. After subsequent hydrogenation, ,-disubstituted amide derivatives were obtained in good yields. Migratory insertion of -oxo palladium carbene species, generated by intermolecular oxidation, is proposed as the key step in this reaction. The study demonstrates the potential of ynamides to serve as carbene precursors in palladium-catalyzed C-C bond-forming cross-coupling reactions. |
| 语种 | 英语 |
| WOS记录号 | WOS:000426252400035 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/45699]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wang, Jianbo |
| 作者单位 | 1.Peking Univ, Coll Chem, Minist Educ, BNLMS, Beijing 100871, Peoples R China 2.Peking Univ, Coll Chem, Minist Educ, Lab Bioorgan Chem & Mol Engn, Beijing 100871, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gao, Yunpeng,Wu, Guojiao,Zhou, Qi,et al. Palladium-Catalyzed Oxygenative Cross-Coupling of Ynamides and Benzyl Bromides by Carbene Migratory Insertion[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2018,57(10):2716-2720. |
| APA | Gao, Yunpeng,Wu, Guojiao,Zhou, Qi,&Wang, Jianbo.(2018).Palladium-Catalyzed Oxygenative Cross-Coupling of Ynamides and Benzyl Bromides by Carbene Migratory Insertion.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,57(10),2716-2720. |
| MLA | Gao, Yunpeng,et al."Palladium-Catalyzed Oxygenative Cross-Coupling of Ynamides and Benzyl Bromides by Carbene Migratory Insertion".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 57.10(2018):2716-2720. |
入库方式： OAI收割
来源：化学研究所
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