Controllable and Reproducible Sheath of Carbon Fibers with Single-Walled Carbon Nanotubes through Electrophoretic Deposition for In Vivo Electrochemical Measurements
文献类型：期刊论文
| 作者 | Xiao, Tongfang1,2; Jiang, Yanan1,2; Ji, Wenliang1; Mao, Lanqun1,2 |
| 刊名 | ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2018-04-03 |
| 卷号 | 90期号:7页码:4840-4846 |
| ISSN号 | 0003-2700 |
| DOI | 10.1021/acs.analchem.8b00303 |
| 英文摘要 | The unique electronic and chemical structures of carbon nanotubes (CNTs) have well enabled their applications in electrochemistry and electroanalytical chemistry; however, the difficulty in reproducibly confining CNTs onto substrate electrodes, particularly onto microelectrodes, still remains to be addressed. In this study, we develop a method to reproducibly confine single-walled carbon nanotubes (SWNTs) onto carbon fiber microelectrodes (CFEs) with electrophoretic deposition (EPD) for in vivo measurement of ascorbate. Under 2.5 V, acid-treated SWNTs are uniformly deposited on CFEs. After thermal treatment at 300 degrees C followed by electrochemical treatment in 0.5 M H2SO4, the SWNT-sheathed CFEs exhibit good activity to accelerate the electrochemical oxidation of ascorbic acid (i.e., ascorbate, in a neutral solution) at an onset potential of -0.15 V vs Ag/AgCl and could in vivo selectively detect ascorbate. The controllable procedures employed for EPD and pretreatment avoid the deviation in the conventional manual modification methods such as drop casting and hand rolling previously used for confining SWNTs onto an electrode surface. With the electrodes prepared here, we find that level of extracellular ascorbate in the rat cortex increases by 20.4 +/- 4.8% (n = 4), relative to its basal level, within 9 min after infusion of kainic acid into the hippocampus to evoke epilepsy. This study offers a reproducible method to prepare SWNT-sheathed CFEs for in vivo monitoring ascorbate that would largely facilitate future studies on neurochemical processes of ascorbate in various physiological and pathological events. |
| 语种 | 英语 |
| 出版者 | AMER CHEMICAL SOC |
| WOS记录号 | WOS:000429385800082 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/45935]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Mao, Lanqun |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Key Lab Analyt Chem Living Biosyst, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xiao, Tongfang,Jiang, Yanan,Ji, Wenliang,et al. Controllable and Reproducible Sheath of Carbon Fibers with Single-Walled Carbon Nanotubes through Electrophoretic Deposition for In Vivo Electrochemical Measurements[J]. ANALYTICAL CHEMISTRY,2018,90(7):4840-4846. |
| APA | Xiao, Tongfang,Jiang, Yanan,Ji, Wenliang,&Mao, Lanqun.(2018).Controllable and Reproducible Sheath of Carbon Fibers with Single-Walled Carbon Nanotubes through Electrophoretic Deposition for In Vivo Electrochemical Measurements.ANALYTICAL CHEMISTRY,90(7),4840-4846. |
| MLA | Xiao, Tongfang,et al."Controllable and Reproducible Sheath of Carbon Fibers with Single-Walled Carbon Nanotubes through Electrophoretic Deposition for In Vivo Electrochemical Measurements".ANALYTICAL CHEMISTRY 90.7(2018):4840-4846. |
入库方式： OAI收割
来源：化学研究所
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