Ovalbumin-stabilized gold nanoclusters with ascorbic acid as reducing agent for detection of serum copper
文献类型：期刊论文
| 作者 | Chen, Yifan1,3; Qiao, Juan1,2; Liu, Qianrong1,4; Qi, Li1,2 |
| 刊名 | CHINESE CHEMICAL LETTERS
 |
| 出版日期 | 2018-03-01 |
| 卷号 | 29期号:3页码:366-370 |
| ISSN号 | 1001-8417 |
| 关键词 | Ovalbumin-stabilized Gold Nanoclusters Fluorescent Probe Ascorbic Acid Reducing Agent Serum Copper |
| DOI | 10.1016/j.cclet.2017.10.014 |
| 英文摘要 | Ovalbumin-stabilized gold nanoclusters (OVA@AuNCs) were prepared with-ascorbic acid as a reducing agent. This strategy could realize the synthesis of water-soluble OVA@AuNCs within 20 min. The as prepared fluorescent probe showed a red fluorescence emission at 630 nm. Moreover, the properties of the OVA@AuNCs were characterized by transmission electron microscope, dynamic light scattering, ultraviolet-visible spectroscopy, fluorescent spectroscopy. Based on the surface electron density decrease-induced fluorescence quenching mechanism, the OVA@AuNCs provided high sensitivity and selectivity for sensing copper ions. A good linear relationship was obtained between the fluorescence intensity of OVA@AuNCs and the concentration of copper ions in the range of 5.0-100.0 mu mol/L (R-2=0.999) with a detection limit of 640 nmol/L. Furthermore, the rat serum copper contents were determined by using the OVA@AuNCs based assay, indicating great potential of fluorescent probes for application in biological and clinical analysis. (C) 2017 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved. |
| 语种 | 英语 |
| 出版者 | ELSEVIER SCIENCE INC |
| WOS记录号 | WOS:000429392800006 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/45999]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Qi, Li |
| 作者单位 | 1.Chinese Acad Sci, Beijing Natl Lab Mol Sci, Key Lab Analyt Chem Living Biosyst, Inst Chem, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Jilin Univ, Zhuhai Coll, Zhuhai 519041, Peoples R China 4.Xian Univ Sci & Technol, Xian 710054, Shaanxi, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Yifan,Qiao, Juan,Liu, Qianrong,et al. Ovalbumin-stabilized gold nanoclusters with ascorbic acid as reducing agent for detection of serum copper[J]. CHINESE CHEMICAL LETTERS,2018,29(3):366-370. |
| APA | Chen, Yifan,Qiao, Juan,Liu, Qianrong,&Qi, Li.(2018).Ovalbumin-stabilized gold nanoclusters with ascorbic acid as reducing agent for detection of serum copper.CHINESE CHEMICAL LETTERS,29(3),366-370. |
| MLA | Chen, Yifan,et al."Ovalbumin-stabilized gold nanoclusters with ascorbic acid as reducing agent for detection of serum copper".CHINESE CHEMICAL LETTERS 29.3(2018):366-370. |
入库方式： OAI收割
来源：化学研究所
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