Exploring the optimal ratio of D-glucose/L-aspartic acid for targeting carbon dots toward brain tumor cells
文献类型：期刊论文
| 作者 | Qiao, Lihong1; Sun, Tingting2,3; Zheng, Xiaohua2,3; Zheng, Min1; Xie, Zhigang2 |
| 刊名 | MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
 |
| 出版日期 | 2018-04-01 |
| 卷号 | 85页码:1-6 |
| ISSN号 | 0928-4931 |
| 关键词 | Optimal Ratio D-glucose L-aspartic Acid Carbon Dots Targeting Brain Cancer |
| DOI | 10.1016/j.msec.2017.12.011 |
| 英文摘要 | Targeting imaging to the desired site of action can increase the accuracy and effectiveness of diagnostic and treatment. In this work, a series of fluorescent carbon dots (CDs) were prepared by varying molar ratios of D-glucose (Glu) to L-aspartic acid (Asp). Their photophysical properties, morphologies and structures were investigated in detail. More important, the targeting ability was screened by confocal laser scanning microscopy and flow cytometry. The results indicate that CDs prepared from the optimal molar ratio of Glu/Asp (7:3) exhibit the highest targeting ability on C6 glioma cells, This work highlights the interplay of molecular design and corresponding functions, and open new possibility of developing state-of-art nanoparticles for biomedical applications. |
| 语种 | 英语 |
| 出版者 | ELSEVIER SCIENCE BV |
| WOS记录号 | WOS:000428496400001 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/46131]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Zheng, Min; Xie, Zhigang |
| 作者单位 | 1.Changchun Univ Technol, Sch Chem & Life Sci, Adv Inst Mat Sci, 2055 Yanan St, Changchun 130012, Jilin, Peoples R China 2.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, 5625 Renmin St, Changchun 130022, Jilin, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qiao, Lihong,Sun, Tingting,Zheng, Xiaohua,et al. Exploring the optimal ratio of D-glucose/L-aspartic acid for targeting carbon dots toward brain tumor cells[J]. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,2018,85:1-6. |
| APA | Qiao, Lihong,Sun, Tingting,Zheng, Xiaohua,Zheng, Min,&Xie, Zhigang.(2018).Exploring the optimal ratio of D-glucose/L-aspartic acid for targeting carbon dots toward brain tumor cells.MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,85,1-6. |
| MLA | Qiao, Lihong,et al."Exploring the optimal ratio of D-glucose/L-aspartic acid for targeting carbon dots toward brain tumor cells".MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 85(2018):1-6. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。