中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
A fluorescence 'turn-on' detection of alpha-ketoglutaric acid with silole as the fluorescence reporter

文献类型:期刊论文

作者Zhan, Chi1,2; Zhang, Guanxin1; Zhang, Deqing1,2
刊名JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
出版日期2018-03-15
卷号355页码:366-370
关键词Fluorescent Detection Aggregation Induced Emission Silole Alpha-ketoglutaric Acid
ISSN号1010-6030
DOI10.1016/j.jphotochem.2017.08.017
英文摘要The selective and sensitive detection of alpha-ketoglutaric acid (KA) is of great importance not only for biological studies but also for early diagnosis of cancers. In comparison with other assays, fluorescence detection is advantageous. However, the fluorescence turn-on detection of KA remains rare. in this paper, we disclose a new fluorescence detection of KA with the ensemble of silole-A and n-octanohydrazide by utilizing the aggregation induced emission feature of silole compounds and the chemical reaction between KA and n-octanohydrazide. The ensemble displays reasonably good sensitivity and selectivity toward KA, and KA with concentration as low as 1.5 mu M can be detected. (C) 2017 Elsevier B.V. All rights reserved.
语种英语
WOS记录号WOS:000428227500053
出版者ELSEVIER SCIENCE SA
源URL[http://ir.iccas.ac.cn/handle/121111/46163]  
专题中国科学院化学研究所
通讯作者Zhang, Guanxin; Zhang, Deqing
作者单位1.Chinese Acad Sci, Inst Chem, CAS Res Educ Ctr Excellence Mol Sci, CAS Key Lab Organ Solids, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
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Zhan, Chi,Zhang, Guanxin,Zhang, Deqing. A fluorescence 'turn-on' detection of alpha-ketoglutaric acid with silole as the fluorescence reporter[J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY,2018,355:366-370.
APA Zhan, Chi,Zhang, Guanxin,&Zhang, Deqing.(2018).A fluorescence 'turn-on' detection of alpha-ketoglutaric acid with silole as the fluorescence reporter.JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY,355,366-370.
MLA Zhan, Chi,et al."A fluorescence 'turn-on' detection of alpha-ketoglutaric acid with silole as the fluorescence reporter".JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY 355(2018):366-370.

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来源:化学研究所

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