Surface functionalization of styrenic block copolymer elastomeric biomaterials with hyaluronic acid via a "grafting to" strategy
文献类型：期刊论文
| 作者 | Li, Xiaomeng1,2; Luan, Shifang1; Yuan, Shuaishuai1,2; Song, Lingjie1,2; Zhao, Jie1,2; Ma, Jiao1,2; Shi, Hengchong1; Yang, Huawei1; Jin, Jing1; Yin, Jinghua1 |
| 刊名 | COLLOIDS AND SURFACES B-BIOINTERFACES
 |
| 出版日期 | 2013-12-01 |
| 卷号 | 112页码:146-154 |
| 关键词 | Styrenic Block Copolymer (Sbc) Hyaluronic Acid (Ha) Surface Functionalization Hemocompatibility Cytocompatibility |
| ISSN号 | 0927-7765 |
| DOI | 10.1016/j.colsurfb.2013.07.048 |
| 英文摘要 | As a biostable elastomer, the hydrophobicity of styrenic block copolymer (SBC) intensely limits its biomedical applications. In order to overcome such shortcoming, the SBC films were grafted with hyaluronic acid (HA) using a coupling agent. The surface chemistry of the modified films was examined by ATR-FTIR and XPS techniques, and the surface morphology was visually described by AFM. The biological performances of the HA-modified films were evaluated by a series of experiments, such as protein adsorption, platelet adhesion, and in vitro cytocompatibility. It was found that the HA-modified samples showed a low adhesiveness to fibroblast at the initial stage; however, it stimulated the growth of fibroblast. The L929 fibroblast growth presented a strong dependence on the molecular weight (MW) of HA. The samples modified with 17 kDa HA exhibited the worst wettability and platelet adhesion, while providing the best results of supporting fibroblast proliferation. (C) 2013 Elsevier B.V. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000328593100022 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/46661]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Luan, Shifang |
| 作者单位 | 1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Xiaomeng,Luan, Shifang,Yuan, Shuaishuai,et al. Surface functionalization of styrenic block copolymer elastomeric biomaterials with hyaluronic acid via a "grafting to" strategy[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2013,112:146-154. |
| APA | Li, Xiaomeng.,Luan, Shifang.,Yuan, Shuaishuai.,Song, Lingjie.,Zhao, Jie.,...&Yin, Jinghua.(2013).Surface functionalization of styrenic block copolymer elastomeric biomaterials with hyaluronic acid via a "grafting to" strategy.COLLOIDS AND SURFACES B-BIOINTERFACES,112,146-154. |
| MLA | Li, Xiaomeng,et al."Surface functionalization of styrenic block copolymer elastomeric biomaterials with hyaluronic acid via a "grafting to" strategy".COLLOIDS AND SURFACES B-BIOINTERFACES 112(2013):146-154. |
入库方式： OAI收割
来源：化学研究所
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