中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Functionalized polypropylene non-woven fabric membrane with bovine serum albumin and its hemocompatibility enhancement

文献类型:期刊论文

作者Zhang, Chang1,2; Jin, Jing1,2; Zhao, Jie1; Jiang, Wei1; Yin, Jinghua1
刊名COLLOIDS AND SURFACES B-BIOINTERFACES
出版日期2013-02-01
卷号102页码:45-52
关键词Hemocompatibility Surface Modification Polypropylene Non-woven Fabric Membrane Uv-irradiated Poly(Acrylic Acid) Bovine Serum Albumin
ISSN号0927-7765
DOI10.1016/j.colsurfb.2012.08.007
英文摘要Bovine serum albumin (BSA) was successfully immobilized onto polypropylene non-woven fabric (PPNWF) membranes using poly(acrylic acid) (PAA) as a spacer. Firstly, O-2 plasma treatment and UV-irradiated technique were combined to graft PM onto the membranes. BSA was then immobilized onto the PAA grafted surface through the coupling of amino groups of BSA to the carboxyl groups of PM. The immobilization of PM and BSA onto the membrane was confirmed by attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR), X-ray photoelectron spectroscopy (XPS), and water contact angle measurement. The water contact angle measurement results revealed that the membrane hydrophilicity improved after modification with PAA and BSA. After BSA immobilization, the amount of protein adsorption and the number of platelet adhesion on the modified membrane significantly decreased, which indicated that hemocompatibility had been considerably improved compared with neat and PM grafted PPNWF. The whole blood clotting time measurement showed that the anticoagulant property of the modified membrane was also significantly enhanced. Crown Copyright (c) 2012 Published by Elsevier B.V. All rights reserved.
语种英语
WOS记录号WOS:000313301200007
出版者ELSEVIER SCIENCE BV
源URL[http://ir.iccas.ac.cn/handle/121111/46663]  
专题中国科学院化学研究所
通讯作者Jiang, Wei
作者单位1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Chang,Jin, Jing,Zhao, Jie,et al. Functionalized polypropylene non-woven fabric membrane with bovine serum albumin and its hemocompatibility enhancement[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2013,102:45-52.
APA Zhang, Chang,Jin, Jing,Zhao, Jie,Jiang, Wei,&Yin, Jinghua.(2013).Functionalized polypropylene non-woven fabric membrane with bovine serum albumin and its hemocompatibility enhancement.COLLOIDS AND SURFACES B-BIOINTERFACES,102,45-52.
MLA Zhang, Chang,et al."Functionalized polypropylene non-woven fabric membrane with bovine serum albumin and its hemocompatibility enhancement".COLLOIDS AND SURFACES B-BIOINTERFACES 102(2013):45-52.

入库方式: OAI收割

来源:化学研究所

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