Improved biocompatibility of poly (styrene-b-(ethylene-co-butylene)-b-styrene) elastomer by a surface graft polymerization of hyaluronic acid
文献类型:期刊论文
作者 | Li, Xiaomeng1,3; Luan, Shifang1; Shi, Hengchong1; Yang, Huawei1,3; Song, Lingjie1,3; Jin, Jing1,3; Yin, Jinghua1; Stagnaro, Paola2 |
刊名 | COLLOIDS AND SURFACES B-BIOINTERFACES
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出版日期 | 2013-02-01 |
卷号 | 102页码:210-217 |
关键词 | Glycidyl Methacrylate-hyaluronic Acid (Gmha) Uv-induced Graft Polymerization Poly (Styrene-b-(Ethylene-co-butylene)-b-styrene) (Sebs) Platelet Adhesion Cytocompatibility |
ISSN号 | 0927-7765 |
DOI | 10.1016/j.colsurfb.2012.08.010 |
英文摘要 | Hyaluronic acid (HA) is an important component of extracellular matrix (ECM) in many tissues, providing a hemocompatible and supportive environment for cell growth. In this study, glycidyl methacrylate-hyaluronic acid (GMHA) was first synthesized and verified by proton nuclear magnetic resonance (H-1 NMR) spectroscopy. GMHA was then grafted to the surface of biomedical elastomer poly (styrene-b-(ethylene-co-butylene)-b-styrene) (SEBS) via an UV-initiated polymerization, monitored by attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and X-ray photoelectron spectroscopy (XPS). The further improvement of biocompatibility of the GMHA-modified SEBS films was assessed by platelet adhesion experiments and in vitro response of murine osteoblastic cell line MC-3T3-E1 with the virgin SEBS surface as the reference. It showed that the surface modification with HA strongly resisted platelet adhesion whereas improved cell-substrate interactions. (c) 2012 Elsevier B.V. All rights reserved. |
语种 | 英语 |
WOS记录号 | WOS:000313301200031 |
出版者 | ELSEVIER SCIENCE BV |
源URL | [http://ir.iccas.ac.cn/handle/121111/47045] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Luan, Shifang |
作者单位 | 1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 2.CNR, Ist Studio Macromol, I-16149 Genoa, Italy 3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Li, Xiaomeng,Luan, Shifang,Shi, Hengchong,et al. Improved biocompatibility of poly (styrene-b-(ethylene-co-butylene)-b-styrene) elastomer by a surface graft polymerization of hyaluronic acid[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2013,102:210-217. |
APA | Li, Xiaomeng.,Luan, Shifang.,Shi, Hengchong.,Yang, Huawei.,Song, Lingjie.,...&Stagnaro, Paola.(2013).Improved biocompatibility of poly (styrene-b-(ethylene-co-butylene)-b-styrene) elastomer by a surface graft polymerization of hyaluronic acid.COLLOIDS AND SURFACES B-BIOINTERFACES,102,210-217. |
MLA | Li, Xiaomeng,et al."Improved biocompatibility of poly (styrene-b-(ethylene-co-butylene)-b-styrene) elastomer by a surface graft polymerization of hyaluronic acid".COLLOIDS AND SURFACES B-BIOINTERFACES 102(2013):210-217. |
入库方式: OAI收割
来源:化学研究所
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