Recent Progress of Molecular Imaging Probes Based on Gadofullerenes
文献类型：期刊论文
| 作者 | Zheng Jun-Peng; Zhen Ming-Ming; Wang Chun-Ru; Shu Chun-Ying |
| 刊名 | CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2012-10-01 |
| 卷号 | 40期号:10页码:1607-1614 |
| 关键词 | Molecular Imaging Endohedral Metallofullerene Magnetic Resonance Imaging Review |
| ISSN号 | 0253-3820 |
| DOI | 10.1016/S1872-2040(11)60581-1 |
| 英文摘要 | Paramagnetic gadofullerenes and their derivatives exhibit more advantages than commercial Magnevist (TM) (Gd-DTPA) therefore have become competitive candidates for MR imaging probes. One of the most important properties is the stable fullerene cages are believed to hinder both chemical attacks on the inner clusters and the escape of the toxic lanthanide ions, which should effectively suppress the toxicity of naked Gd3+ ions. Some functionalized gadofullerides are also available for further conjugation to fabricate multifunctional probes. This review presented the latest findings of MRI imaging probes based on various gadofullerenes, including Gd@C-60, Gd@C-82 and Gd3N@C-80 and discussed the derivative strategy of gadofullerenes determining their relaxivity properties, biodistributions as well as their potential applications as nanoplatform for multifunctional probes. |
| 语种 | 英语 |
| WOS记录号 | WOS:000311485100007 |
| 出版者 | ELSEVIER SCIENCE INC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/47615]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Shu Chun-Ying |
| 作者单位 | Chinese Acad Sci, Inst Chem, Key Lab Mol Nanostruct & Nanotechnol, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zheng Jun-Peng,Zhen Ming-Ming,Wang Chun-Ru,et al. Recent Progress of Molecular Imaging Probes Based on Gadofullerenes[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2012,40(10):1607-1614. |
| APA | Zheng Jun-Peng,Zhen Ming-Ming,Wang Chun-Ru,&Shu Chun-Ying.(2012).Recent Progress of Molecular Imaging Probes Based on Gadofullerenes.CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,40(10),1607-1614. |
| MLA | Zheng Jun-Peng,et al."Recent Progress of Molecular Imaging Probes Based on Gadofullerenes".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 40.10(2012):1607-1614. |
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来源：化学研究所
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