Cyclopentadiene-Phosphine/Palladium-Catalyzed Cleavage of C-N Bonds in Secondary Amines: Synthesis of Pyrrole and Indole Derivatives from Secondary Amines and Alkenyl or Aryl Dibromides
文献类型：期刊论文
| 作者 | Geng, Weizhi1,2; Zhang, Wen-Xiong1,2; Hao, Wei1,2; Xi, Zhenfeng1,2,3 |
| 刊名 | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
 |
| 出版日期 | 2012-12-19 |
| 卷号 | 134期号:50页码:20230-20233 |
| ISSN号 | 0002-7863 |
| DOI | 10.1021/ja308950d |
| 英文摘要 | An efficient Pd-catalyzed cleavage of C(sp(3))-N bonds in secondary amines and a consequent C(sp(2))-N and C(sp(3))-N coupling process was developed. Various secondary amines could be used to react with alkenyl or aryl dibromides, affording pyrroles and indoles in high yields. Cyclopentadiene-phosphine ligands, a new type of P-olefin ligand, were found to be able to promote the efficiency of this Pd-catalyzed process remarkably. A reactive Pd complex coordinated with a cyclopentadiene-phosphine ligand was successfully isolated and structurally characterized. |
| 语种 | 英语 |
| WOS记录号 | WOS:000312430700006 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/47631]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Xi, Zhenfeng |
| 作者单位 | 1.Peking Univ, Coll Chem, Minist Educ, BNLMS, Beijing 100871, Peoples R China 2.Peking Univ, Coll Chem, Minist Educ, Key Lab Bioorgan Chem & Mol Engn, Beijing 100871, Peoples R China 3.Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China |
| 推荐引用方式 GB/T 7714 | Geng, Weizhi,Zhang, Wen-Xiong,Hao, Wei,et al. Cyclopentadiene-Phosphine/Palladium-Catalyzed Cleavage of C-N Bonds in Secondary Amines: Synthesis of Pyrrole and Indole Derivatives from Secondary Amines and Alkenyl or Aryl Dibromides[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2012,134(50):20230-20233. |
| APA | Geng, Weizhi,Zhang, Wen-Xiong,Hao, Wei,&Xi, Zhenfeng.(2012).Cyclopentadiene-Phosphine/Palladium-Catalyzed Cleavage of C-N Bonds in Secondary Amines: Synthesis of Pyrrole and Indole Derivatives from Secondary Amines and Alkenyl or Aryl Dibromides.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,134(50),20230-20233. |
| MLA | Geng, Weizhi,et al."Cyclopentadiene-Phosphine/Palladium-Catalyzed Cleavage of C-N Bonds in Secondary Amines: Synthesis of Pyrrole and Indole Derivatives from Secondary Amines and Alkenyl or Aryl Dibromides".JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 134.50(2012):20230-20233. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。