Study of STAT3 G-quadruplex folding patterns by CD spectroscopy and molecular modeling
文献类型：期刊论文
| 作者 | Lin, Sen2; Xu, Ming1; Yuan, Gu2 |
| 刊名 | CHINESE CHEMICAL LETTERS
 |
| 出版日期 | 2012-03-01 |
| 卷号 | 23期号:3页码:329-331 |
| 关键词 | G-quadruplex Stat3 Gene Cd Spectroscopy Molecular Modeling |
| ISSN号 | 1001-8417 |
| DOI | 10.1016/j.cclet.2011.11.002 |
| 英文摘要 | The G-quadruplexes formed from G-rich strands in the telomere and oncogene-promoter regions are regarded as new promising targets in the cancer therapy. A G-quadruplex in the downstream flanking region of the signal transducer and activator of transcription 3 (STAT3) gene was explored. Its folding patterns were proposed to be 3:2:2 and 3:3:1 loop isomers by the mutation analysis by CD spectroscopy. The structures were constructed and refined by molecular modeling method. (C) 2012 Gu Yuan. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000301631500020 |
| 出版者 | ELSEVIER SCIENCE INC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/47641]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Xu, Ming |
| 作者单位 | 1.Peking Univ, Hosp 3, Minist Educ, Key Lab Mol Cardiovasc Sci,Inst Vasc Med, Beijing 100191, Peoples R China 2.Peking Univ, Key Lab Bioorgan Chem & Mol Engn, Coll Chem & Mol Engn, Minist Educ,Dept Chem Biol,BNLMS, Beijing 100871, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lin, Sen,Xu, Ming,Yuan, Gu. Study of STAT3 G-quadruplex folding patterns by CD spectroscopy and molecular modeling[J]. CHINESE CHEMICAL LETTERS,2012,23(3):329-331. |
| APA | Lin, Sen,Xu, Ming,&Yuan, Gu.(2012).Study of STAT3 G-quadruplex folding patterns by CD spectroscopy and molecular modeling.CHINESE CHEMICAL LETTERS,23(3),329-331. |
| MLA | Lin, Sen,et al."Study of STAT3 G-quadruplex folding patterns by CD spectroscopy and molecular modeling".CHINESE CHEMICAL LETTERS 23.3(2012):329-331. |
入库方式： OAI收割
来源：化学研究所
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