Design and Synthesis of Janus-Type Chiral Dendritic Diphosphanes and Their Applications in Asymmetric Hydrogenation
文献类型：期刊论文
| 作者 | Liu, Ji1,2; Feng, Yu1,2; Ma, Baode1,2; He, Yan-Mei1,2; Fan, Qing-Hua1,2 |
| 刊名 | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
 |
| 出版日期 | 2012-12-01 |
| 期号 | 34页码:6737-6744 |
| ISSN号 | 1434-193X |
| 关键词 | Asymmetric Catalysis Dendrimers Phosphane Ligands Hydrogenation Catalyst Recycling |
| DOI | 10.1002/ejoc.201200999 |
| 英文摘要 | A series of chiral diphosphane-functionalized Janus dendrimers (up to 16 BINAP units) have been readily synthesized by using liquid-phase organic synthesis with the third-generation Frechet-type poly(aryl ether) dendron as the soluble support. The resulting dendritic ligands were purified by simple solvent precipitation without the need for chromatographic separation at the end of reaction. Complete functionalization of the dendrimers with BINAP moieties was confirmed by 1H NMR, MALDI-TOF mass spectroscopy, and elemental analyses. Their ruthenium complexes were applied to the asymmetric hydrogenation of 2-arylacrylic acids. It was found that only slightly lower enantioselectivities were achieved than the corresponding small-molecular Ru catalyst. Interestingly, a clear increase in activity of the dendritic catalysts was observed on going to the higher generations. In addition, the third-generation catalyst could be recycled without significant loss of catalytic activity or enantioselectivity before the fifth catalytic run. |
| 语种 | 英语 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| WOS记录号 | WOS:000311384800009 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/47665]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Fan, Qing-Hua |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, CAS Key Lab Mol Recognit & Funct, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Ji,Feng, Yu,Ma, Baode,et al. Design and Synthesis of Janus-Type Chiral Dendritic Diphosphanes and Their Applications in Asymmetric Hydrogenation[J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY,2012(34):6737-6744. |
| APA | Liu, Ji,Feng, Yu,Ma, Baode,He, Yan-Mei,&Fan, Qing-Hua.(2012).Design and Synthesis of Janus-Type Chiral Dendritic Diphosphanes and Their Applications in Asymmetric Hydrogenation.EUROPEAN JOURNAL OF ORGANIC CHEMISTRY(34),6737-6744. |
| MLA | Liu, Ji,et al."Design and Synthesis of Janus-Type Chiral Dendritic Diphosphanes and Their Applications in Asymmetric Hydrogenation".EUROPEAN JOURNAL OF ORGANIC CHEMISTRY .34(2012):6737-6744. |
入库方式： OAI收割
来源：化学研究所
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