The development of charge detection-quadrupole ion trap mass spectrometry driven by rectangular and triangular waves
文献类型：期刊论文
| 作者 | Xiong, Caiqiao1,2; Xu, Gaoping3; Zhou, Xiaoyu1,2; Wang, Jianing1,2; Tang, Yin1,2; Chen, Rui1,2; Peng, Wen-Ping4; Chang, Huan-Cheng5; Nie, Zongxiu1,2,6 |
| 刊名 | ANALYST
 |
| 出版日期 | 2012 |
| 卷号 | 137期号:5页码:1199-1204 |
| ISSN号 | 0003-2654 |
| DOI | 10.1039/c2an15756j |
| 英文摘要 | In this article, the charge detection quadrupole mass spectrometry (CD-ITMS) driven by rectangular and triangular waveforms (rect-CD-ITMS and tri-CD-ITMS) was developed for the characterization of microparticles. Since the frequency scan of rectangular and triangular waveform could be realized easier than that of sinusoidal waveform, this research intends to provide simpler operation modes for CD-ITMS. In order to demonstrate the feasibility of rect-CD-ITMS and tri-CD-ITMS, the discharge onset voltage, ejection point of analyzed particles, and the achieved mass resolution were analyzed and compared with the case in conventional sinusoidal CD-ITMS (sin-CD-ITMS). The results indicated that the rect-CD-ITMS and tri-CD-ITMS can work well for the mass measurement of microparticles by using frequency scan. Identical mass resolutions were achieved under the same root mean square (RMS) voltage of different waveforms. The mass resolution was further improved by increasing the applied voltage and signal-to-noise ratio (S/N) of charge detector. Moreover, the rect-CD-ITMS and tri-CD-ITMS were applied to characterize red blood cells (RBCs). According to the obtained mean masses and mass distributions, normal and anemic RBCs were distinguished successfully. |
| 语种 | 英语 |
| WOS记录号 | WOS:000300038400021 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/48259]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Nie, Zongxiu |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Key Lab Analyt Chem Living Biosyst, Beijing 100190, Peoples R China 2.Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China 3.Jiujiang Univ, Sch Sci, Jiujiang 332005, Peoples R China 4.Natl Dong Hwa Univ, Dept Phys, Shoufeng 97401, Hualien, Taiwan 5.Acad Sinica, Inst Atom & Mol Sci, Taipei 106, Taiwan 6.Beijing Ctr Mass Spectrometry, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xiong, Caiqiao,Xu, Gaoping,Zhou, Xiaoyu,et al. The development of charge detection-quadrupole ion trap mass spectrometry driven by rectangular and triangular waves[J]. ANALYST,2012,137(5):1199-1204. |
| APA | Xiong, Caiqiao.,Xu, Gaoping.,Zhou, Xiaoyu.,Wang, Jianing.,Tang, Yin.,...&Nie, Zongxiu.(2012).The development of charge detection-quadrupole ion trap mass spectrometry driven by rectangular and triangular waves.ANALYST,137(5),1199-1204. |
| MLA | Xiong, Caiqiao,et al."The development of charge detection-quadrupole ion trap mass spectrometry driven by rectangular and triangular waves".ANALYST 137.5(2012):1199-1204. |
入库方式： OAI收割
来源：化学研究所
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