One-pot synthesis of hyperbranched glycopolymers by RAFT polymerization
文献类型：期刊论文
| 作者 | Wei, Zhenke1,2,3; Hao, Xiaojuan3; Gan, Zhihua1; Hughes, Timothy C. |
| 刊名 | JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
 |
| 出版日期 | 2012-06-15 |
| 卷号 | 50期号:12页码:2378-2388 |
| 关键词 | Biomimetic Glycopolymer Hyperbranched Inimer Reversible Addition-fragmentation Chain Transfer Polymerization (Raft) |
| ISSN号 | 0887-624X |
| DOI | 10.1002/pola.26012 |
| 英文摘要 | Soluble hyperbranched glycopolymers were prepared by copolymerization of glycan monomers with reversible addition-fragmentation chain transfer polymerization (RAFT) inimers in a simple one-pot reaction. Two novel RAFT inimers, 2-(methacryloyloxy)ethyl 4-cyano-4-(phenylcarbonothioylthio)pentanoate (MAE-CPP) and 2-(3-(benzylthiocarbonothioylthio)propanoyloxy)ethyl acrylate (BCP-EA) were synthesized and used to prepare hyperbranched glycopolymers. Two types of galactose-based saccharide monomers, 6-O-methacryloyl-1,2:3,4-di-O-isopropylidene-D-galactopyranose (proGal-M) and 6-O-(2'-acrylamido-2'-methylpropanoate)-1,2:3,4-di-O-isopropylidene-D-galactopyranose (proGal-A), containing a methacrylate and an acrylamide group, respectively, were also synthesized and polymerized under the mediation of the MAE-CPP and BCP-EA inimers, respectively. In addition, hyperbranched poly(proGal-M), linear poly(proGal-A), and hyperbranched poly(proGal-A) were generated and their polymerization kinetics were studied and compared. An unexpected difference was observed in the kinetics between the two monomers during polymerization: the relationship between polymerization rate and concentration of inimer was totally opposite in the two monomerinimer systems. Branching analysis was conducted by using degree of branching (DB) as the measurement parameter. As expected, a higher DB occurred with increased inimer content. Furthermore, these polymers were readily deprotected by hydrolysis in trifluoroacetic acid solution resulting in water-soluble polymers. The resulting branched glycopolymers have potential as biomimetics of polysaccharides. (c) 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2012 |
| 语种 | 英语 |
| WOS记录号 | WOS:000303758200008 |
| 出版者 | WILEY-BLACKWELL |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/48391]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Gan, Zhihua |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100043, Peoples R China 3.CSIRO, Clayton, Vic 3169, Australia |
| 推荐引用方式 GB/T 7714 | Wei, Zhenke,Hao, Xiaojuan,Gan, Zhihua,et al. One-pot synthesis of hyperbranched glycopolymers by RAFT polymerization[J]. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY,2012,50(12):2378-2388. |
| APA | Wei, Zhenke,Hao, Xiaojuan,Gan, Zhihua,&Hughes, Timothy C..(2012).One-pot synthesis of hyperbranched glycopolymers by RAFT polymerization.JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY,50(12),2378-2388. |
| MLA | Wei, Zhenke,et al."One-pot synthesis of hyperbranched glycopolymers by RAFT polymerization".JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY 50.12(2012):2378-2388. |
入库方式： OAI收割
来源：化学研究所
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