Synthesis of a Bifunctional Fluorescent Polymer for Cell Imaging and Enzyme Detection
文献类型：期刊论文
| 作者 | Wen, Quanshan; Zhu, Chunlei; Liu, Libing; Yang, Qiong; Wang, Shu; Zhu, Daoben |
| 刊名 | MACROMOLECULAR CHEMISTRY AND PHYSICS
 |
| 出版日期 | 2012-12-13 |
| 卷号 | 213期号:23页码:2486-2491 |
| 关键词 | Cationic Conjugated Polymers Cell Imaging Enzyme Fluorescence Sensors |
| ISSN号 | 1022-1352 |
| DOI | 10.1002/macp.201200419 |
| 英文摘要 | A new bifunctional cationic conjugated polyfluorene derivative (PFPBOH) containing phenylboronic acid group has been synthesized and characterized. The phenylfluorenyl backbone and positively charged groups in the side chain give the polymer PFPBOH excellent fluorescence property and good water solubility. Phenylboronic acid moieties on the side chain of the polymer form cyclic esters with adjacent diols on cell membrane, which can be employed in cell imaging. Besides that, the fluorescence of PFPBOH can be quenched by p-nitroaniline released via enzyme reaction, thus, the polymer can be used for ?-glutamyltranspeptidase detection through a fluorescence turn off mechanism. These findings exhibit great potential for developing multifunctional polymer materials for simultaneous imaging and detection. |
| 语种 | 英语 |
| WOS记录号 | WOS:000312656400006 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/48417]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Liu, Libing |
| 作者单位 | Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wen, Quanshan,Zhu, Chunlei,Liu, Libing,et al. Synthesis of a Bifunctional Fluorescent Polymer for Cell Imaging and Enzyme Detection[J]. MACROMOLECULAR CHEMISTRY AND PHYSICS,2012,213(23):2486-2491. |
| APA | Wen, Quanshan,Zhu, Chunlei,Liu, Libing,Yang, Qiong,Wang, Shu,&Zhu, Daoben.(2012).Synthesis of a Bifunctional Fluorescent Polymer for Cell Imaging and Enzyme Detection.MACROMOLECULAR CHEMISTRY AND PHYSICS,213(23),2486-2491. |
| MLA | Wen, Quanshan,et al."Synthesis of a Bifunctional Fluorescent Polymer for Cell Imaging and Enzyme Detection".MACROMOLECULAR CHEMISTRY AND PHYSICS 213.23(2012):2486-2491. |
入库方式： OAI收割
来源：化学研究所
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