Nucleophilic addition of regioselectively lithiated indoline with aldimines for the syntheses of 2-and 7-indolinyl methanamine derivatives
文献类型：期刊论文
| 作者 | Cheng, Liang; Liu, Li; Li, Chuan; Jia, Han; Wang, Dong; Chen, Yong-Jun |
| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2012-08-01 |
| 卷号 | 53期号:31页码:4004-4007 |
| 关键词 | Indoline Ortho-lithiation Para-lithiation Imine Indolinyl Methanamines |
| ISSN号 | 0040-4039 |
| DOI | 10.1016/j.tetlet.2012.05.119 |
| 英文摘要 | Indolines bearing different N-protecting groups (N-Tbf and N-Boc) were deprotonated regioselectively at C-2 (sp(3) hybridized ortho-H) and C-7 (sp(2) hybridized para-H) of the indoline ring, respectively. The generated organolithium intermediates reacted with aldimines to give the desired products in good yields with excellent anti-diastereoselectivities (>99:1). The produced N-Ts-(1-Tbf-indolin-2-yl)methanamine was facilely transformed to a fused heterocyclic compound. (C) 2012 Elsevier Ltd. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000306456300015 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/48489]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Liu, Li |
| 作者单位 | Chinese Acad Sci, Inst Chem, CAS Key Lab Mol Recognit & Funct, BNLMS, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cheng, Liang,Liu, Li,Li, Chuan,et al. Nucleophilic addition of regioselectively lithiated indoline with aldimines for the syntheses of 2-and 7-indolinyl methanamine derivatives[J]. TETRAHEDRON LETTERS,2012,53(31):4004-4007. |
| APA | Cheng, Liang,Liu, Li,Li, Chuan,Jia, Han,Wang, Dong,&Chen, Yong-Jun.(2012).Nucleophilic addition of regioselectively lithiated indoline with aldimines for the syntheses of 2-and 7-indolinyl methanamine derivatives.TETRAHEDRON LETTERS,53(31),4004-4007. |
| MLA | Cheng, Liang,et al."Nucleophilic addition of regioselectively lithiated indoline with aldimines for the syntheses of 2-and 7-indolinyl methanamine derivatives".TETRAHEDRON LETTERS 53.31(2012):4004-4007. |
入库方式： OAI收割
来源：化学研究所
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