A proton shelter inspired by the sugar coating of acidophilic archaea
文献类型：期刊论文
| 作者 | Wang, Xiumei1,2,3; Lv, Bei'er1,3,4; Cai, Guixin1; Fu, Long1; Wu, Yuanzi1; Wang, Xiang5; Ren, Bin5; Ma, Hongwei1 |
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2012-11-27 |
| 卷号 | 2 |
| ISSN号 | 2045-2322 |
| DOI | 10.1038/srep00892 |
| 英文摘要 | The acidophilic archaeons are a group of single-celled microorganisms that flourish in hot acid springs (usually pH < 3) but maintain their internal pH near neutral. Although there is a lack of direct evidence, the abundance of sugar modifications on the cell surface has been suggested to provide the acidophiles with protection against proton invasion. In this study, a hydroxyl (OH)-rich polymer brush layer was prepared to mimic the OH-rich sugar coating. Using a novel pH-sensitive dithioacetal molecule as a probe, we studied the proton-resisting property and found that a 10-nm-thick polymer layer was able to raise the pH from 1.0 to > 5.0, indicating that the densely packed OH-rich layer is a proton shelter. As strong evidence for the role of sugar coatings as proton barriers, this biomimetic study provides insight into evolutionary biology, and the results also could be expanded for the development of biocompatible anti-acid materials. |
| 语种 | 英语 |
| 出版者 | NATURE PUBLISHING GROUP |
| WOS记录号 | WOS:000311708300004 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/48549]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Ma, Hongwei |
| 作者单位 | 1.Chinese Acad Sci, Suzhou Inst Nanotech & Nanobion, Div Nanobiomed, Suzhou 215123, Peoples R China 2.Chinese Acad Sci, Tech Inst Phys & Chem, Beijing 100190, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China 5.Xiamen Univ, Dept Chem, Xiamen 361005, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Xiumei,Lv, Bei'er,Cai, Guixin,et al. A proton shelter inspired by the sugar coating of acidophilic archaea[J]. SCIENTIFIC REPORTS,2012,2. |
| APA | Wang, Xiumei.,Lv, Bei'er.,Cai, Guixin.,Fu, Long.,Wu, Yuanzi.,...&Ma, Hongwei.(2012).A proton shelter inspired by the sugar coating of acidophilic archaea.SCIENTIFIC REPORTS,2. |
| MLA | Wang, Xiumei,et al."A proton shelter inspired by the sugar coating of acidophilic archaea".SCIENTIFIC REPORTS 2(2012). |
入库方式： OAI收割
来源：化学研究所
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