Radiation synthesis and characterization of nanosilver/gelatin/carboxymethyl chitosan hydrogel
文献类型:期刊论文
作者 | Zhou, Ying1,3; Zhao, Yinghui1,3; Wang, Lu1; Xu, Ling1,3; Zhai, Maolin4; Wei, Shicheng2,3 |
刊名 | RADIATION PHYSICS AND CHEMISTRY
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出版日期 | 2012-05-01 |
卷号 | 81期号:5页码:553-560 |
关键词 | Nanosilver Radiation Gelatin Carboxymethyl Chitosan Hydrogel Wound Dressing |
ISSN号 | 0969-806X |
DOI | 10.1016/j.radphyschem.2012.01.014 |
英文摘要 | A series of antibacterial hydrogels were fabricated from an aqueous solution of AgNO3, gelatin and carboxymethyl chitosan (CM-chitosan) by radiation-induced reduction and crosslinking at ambient temperature. The nanosilver particles were in situ synthesized accompanying with the formation of gelatin/CM-chitosan hydrogel. Transmission Electron Microscope and UV-vis analysis have verified the formation and homogeneous distribution of nanosilver particles in the hydrogel matrix. The nanosilver/gelatin/CM-chitosan hydrogels possessed interconnected porous structure, had a compressive modulus of 44 to 56 kPa, and could absorb 62 to 108 times of deionized water to its dry weight. Furthermore, the hydrogels were found to have sound antibacterial effect on Escherichia coli (E. coli), and their antibacterial ability could be significantly enhanced by the increasing of AgNO3 content. The comprehensive results of this study suggest that nanosilver/gelatin/CM-chitosan hydrogels have potential as an antibacterial wound dressing. (C) 2012 Elsevier Ltd. All rights reserved. |
语种 | 英语 |
WOS记录号 | WOS:000302456000011 |
出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
源URL | [http://ir.iccas.ac.cn/handle/121111/48769] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Xu, Ling |
作者单位 | 1.Peking Univ, Coll Engn, Beijing 100871, Peoples R China 2.Peking Univ, Dept Oral & Maxillofacial Surg, Sch & Hosp Stomatol, Beijing 100081, Peoples R China 3.Peking Univ, Ctr Biomed Mat & Tissue Engn, Acad Adv Interdisciplinary Studies, Beijing 100871, Peoples R China 4.Peking Univ, Beijing Natl Lab Mol Sci, Dept Appl Chem, Coll Chem & Mol Engn, Beijing 100871, Peoples R China |
推荐引用方式 GB/T 7714 | Zhou, Ying,Zhao, Yinghui,Wang, Lu,et al. Radiation synthesis and characterization of nanosilver/gelatin/carboxymethyl chitosan hydrogel[J]. RADIATION PHYSICS AND CHEMISTRY,2012,81(5):553-560. |
APA | Zhou, Ying,Zhao, Yinghui,Wang, Lu,Xu, Ling,Zhai, Maolin,&Wei, Shicheng.(2012).Radiation synthesis and characterization of nanosilver/gelatin/carboxymethyl chitosan hydrogel.RADIATION PHYSICS AND CHEMISTRY,81(5),553-560. |
MLA | Zhou, Ying,et al."Radiation synthesis and characterization of nanosilver/gelatin/carboxymethyl chitosan hydrogel".RADIATION PHYSICS AND CHEMISTRY 81.5(2012):553-560. |
入库方式: OAI收割
来源:化学研究所
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