Wound Healing Assay Using Microfluidic Channels
文献类型：期刊论文
| 作者 | Xi Yan-li1; Wang Shu-tao2; Su Bin2; Ha Qing1; Niu Feng-lan1; Nie Fu-qiang2 |
| 刊名 | CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
 |
| 出版日期 | 2012-05-01 |
| 卷号 | 28期号:3页码:472-476 |
| 关键词 | Wound Healing Cell Migration Microfluidic Channel |
| ISSN号 | 1005-9040 |
| 英文摘要 | An approach was described to produce a wound area in vitro using laminar flow technique to selectively remove cells in microfluidic channels. Cell migration which plays an important role in the process of wound healing can be observed dynamically by this method. In order to prove our system, we have studied its properties by injecting NIH-3T3 cells into main channel and added several reagents to observe the mediatory influence. The results reveal that fibroblast growth factor-2(FGF-2), insulin-like growth factor 1(IGF-I), platelet-derived growth factor BB(PDGF-BB) and ascorbic acid(Vc) groups can promote cell migration compared with the control group. But the average migration distance was diminished in dexamethasone group. It can be concluded that this system can be used to analyze the process of wound healing. |
| 语种 | 英语 |
| WOS记录号 | WOS:000305315100025 |
| 出版者 | HIGHER EDUCATION PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/48829]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Niu Feng-lan |
| 作者单位 | 1.Jinlin Univ, Sch Publ Hlth, Changchun 130021, Peoples R China 2.Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, BNLMS, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xi Yan-li,Wang Shu-tao,Su Bin,et al. Wound Healing Assay Using Microfluidic Channels[J]. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,2012,28(3):472-476. |
| APA | Xi Yan-li,Wang Shu-tao,Su Bin,Ha Qing,Niu Feng-lan,&Nie Fu-qiang.(2012).Wound Healing Assay Using Microfluidic Channels.CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,28(3),472-476. |
| MLA | Xi Yan-li,et al."Wound Healing Assay Using Microfluidic Channels".CHEMICAL RESEARCH IN CHINESE UNIVERSITIES 28.3(2012):472-476. |
入库方式： OAI收割
来源：化学研究所
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