中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 化学研究所
  3. 中国科学院化学研究所
Synthesis and characterization of Sant-75 derivatives as Hedgehog-pathway inhibitors

文献类型：期刊论文

作者Che, Chao1,2; Li, Song1,2; Yang, Bo1; Xin, Shengchang1; Yu, Zhixiong1; Shao, Taofeng1; Tao, Chuanye1; Lin, Shuo1,3; Yang, Zhen1,4,5
刊名BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
出版日期2012-06-06
卷号8页码:841-849
关键词Chemical Diversity Diversity-oriented Hedgehog Pathway Inhibitor Sant-75 Synthesis
ISSN号1860-5397
DOI10.3762/bjoc.8.94
英文摘要Sant-75 is a newly identified potent inhibitor of the hedgehog pathway. We designed a diversity-oriented synthesis program, and synthesized a series of Sant-75 analogues, which lays the foundation for further investigation of the structure-activity relationship of this important class of hedgehog-pathway inhibitors.
语种英语
WOS记录号WOS:000305074600003
出版者BEILSTEIN-INSTITUT
源URL[http://ir.iccas.ac.cn/handle/121111/48843]  
专题中国科学院化学研究所
通讯作者Lin, Shuo
作者单位1.Peking Univ, Shenzhen Grad Sch, Sch Chem Biol & Biotechnol, Lab Chem Genom, Shenzhen 518055, Peoples R China
2.Shenzhen Shengjie Biotech Co Ltd, Shenzhen 518055, Peoples R China
3.Univ Calif Los Angeles, Dept Mol Cell & Dev Biol, Los Angeles, CA USA
4.Peking Univ, Coll Chem, Beijing Natl Lab Mol Sci BNLMS, Beijing 100871, Peoples R China
5.Minist Educ, Key Lab Bioorgan Chem & Mol Engn, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714		 Che, Chao,Li, Song,Yang, Bo,et al. Synthesis and characterization of Sant-75 derivatives as Hedgehog-pathway inhibitors[J]. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY,2012,8:841-849.
APA Che, Chao.,Li, Song.,Yang, Bo.,Xin, Shengchang.,Yu, Zhixiong.,...&Yang, Zhen.(2012).Synthesis and characterization of Sant-75 derivatives as Hedgehog-pathway inhibitors.BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY,8,841-849.
MLA Che, Chao,et al."Synthesis and characterization of Sant-75 derivatives as Hedgehog-pathway inhibitors".BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY 8(2012):841-849.

入库方式： OAI收割

来源：化学研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。