Antitumor activity of folate-targeted, paclitaxel-loaded polymeric micelles on a human esophageal EC9706 cancer cell line
文献类型：期刊论文
| 作者 | Wu, Wenbin1; Zheng, Yonghui2; Wang, Rui2; Huang, Weili3; Liu, Lei2; Hu, Xiuli2; Liu, Shi2; Yue, Jun2; Tong, Ti1; Jing, Xiabin2 |
| 刊名 | INTERNATIONAL JOURNAL OF NANOMEDICINE
 |
| 出版日期 | 2012 |
| 卷号 | 7页码:3487-3502 |
| 关键词 | Esophageal Cancer Folate Paclitaxel Polymer-drug Conjugate Targeted Drug Delivery |
| ISSN号 | 1178-2013 |
| DOI | 10.2147/IJN.S32620 |
| 英文摘要 | Background: Esophageal cancer is recognized as one of the most refractory pernicious diseases. In addition, it is an aggressive malignancy with a propensity for local progression and distant dissemination. Because of the poor long-term prognosis for patients with esophageal cancer, increasing attention has focused on the integration of targeted agents into current therapeutics. Nevertheless, there have been few studies reported concerning the therapeutic efficacy of paclitaxel-conjugated polymeric micelles in human esophageal cancer in vivo. Therefore, the aim of this research was to investigate the tumor inhibition effect of composite micelles containing folic acid and paclitaxel on the human esophageal EC9706 cancer cell line. |
| 语种 | 英语 |
| WOS记录号 | WOS:000306103300001 |
| 出版者 | DOVE MEDICAL PRESS LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/49015]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Tong, Ti |
| 作者单位 | 1.Jilin Univ, Dept Thorac Surg, Hosp 2, Changchun 130041, Peoples R China 2.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 3.Beihua Univ, Dept Gastroenterol, Affiliated Hosp, Jilin, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Wenbin,Zheng, Yonghui,Wang, Rui,et al. Antitumor activity of folate-targeted, paclitaxel-loaded polymeric micelles on a human esophageal EC9706 cancer cell line[J]. INTERNATIONAL JOURNAL OF NANOMEDICINE,2012,7:3487-3502. |
| APA | Wu, Wenbin.,Zheng, Yonghui.,Wang, Rui.,Huang, Weili.,Liu, Lei.,...&Jing, Xiabin.(2012).Antitumor activity of folate-targeted, paclitaxel-loaded polymeric micelles on a human esophageal EC9706 cancer cell line.INTERNATIONAL JOURNAL OF NANOMEDICINE,7,3487-3502. |
| MLA | Wu, Wenbin,et al."Antitumor activity of folate-targeted, paclitaxel-loaded polymeric micelles on a human esophageal EC9706 cancer cell line".INTERNATIONAL JOURNAL OF NANOMEDICINE 7(2012):3487-3502. |
入库方式： OAI收割
来源：化学研究所
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