Asymmetric Synthesis of Wieland-Miescher and Hajos-Parrish Ketones Catalyzed by an Amino-Acid-Derived Chiral Primary Amine
文献类型：期刊论文
| 作者 | Zhou, Pengxin; Zhang, Long; Luo, Sanzhong; Cheng, Jin-Pei |
| 刊名 | JOURNAL OF ORGANIC CHEMISTRY
 |
| 出版日期 | 2012-03-02 |
| 卷号 | 77期号:5页码:2526-2530 |
| ISSN号 | 0022-3263 |
| DOI | 10.1021/jo202433v |
| 英文摘要 | This paper describes a simple chiral primary amine-catalyzed highly efficient and practical protocol for the synthesis of both Wieland-Miescher ketone and Hajos-Parrish ketone as well as their analogues. The reaction can be conducted in gram scale with 1% mol catalyst loading producing high enantioselectivity (up to 96% ee) and excellent yields (up to 98%). This procedure represents one of the most efficient methods for the synthesis of these versatile chiral building blocks. |
| 语种 | 英语 |
| WOS记录号 | WOS:000300915900048 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/49331]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Luo, Sanzhong |
| 作者单位 | Chinese Acad Sci, Inst Chem, BNLMS, CAS Key Lab Mol Recognit & Funct, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou, Pengxin,Zhang, Long,Luo, Sanzhong,et al. Asymmetric Synthesis of Wieland-Miescher and Hajos-Parrish Ketones Catalyzed by an Amino-Acid-Derived Chiral Primary Amine[J]. JOURNAL OF ORGANIC CHEMISTRY,2012,77(5):2526-2530. |
| APA | Zhou, Pengxin,Zhang, Long,Luo, Sanzhong,&Cheng, Jin-Pei.(2012).Asymmetric Synthesis of Wieland-Miescher and Hajos-Parrish Ketones Catalyzed by an Amino-Acid-Derived Chiral Primary Amine.JOURNAL OF ORGANIC CHEMISTRY,77(5),2526-2530. |
| MLA | Zhou, Pengxin,et al."Asymmetric Synthesis of Wieland-Miescher and Hajos-Parrish Ketones Catalyzed by an Amino-Acid-Derived Chiral Primary Amine".JOURNAL OF ORGANIC CHEMISTRY 77.5(2012):2526-2530. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。