中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Graphite-Coated Paper as Substrate for High Sensitivity Analysis in Ambient Surface-Assisted Laser Desorption/Ionization Mass Spectrometry

文献类型:期刊论文

作者Zhang, Jialing; Li, Ze; Zhang, Chengsen; Feng, Baosheng; Zhou, Zhigui; Bai, Yu; Liu, Huwei
刊名ANALYTICAL CHEMISTRY
出版日期2012-04-03
卷号84期号:7页码:3296-3301
ISSN号0003-2700
DOI10.1021/ac300002g
英文摘要In this work, an extremely simple and quite sensitive mass spectrometric method termed ambient surface-assisted laser desorption/ionization mass spectrometry (ambient SALDI-MS) was developed to analyze different kinds of compounds, just using a piece of graphite-coated paper for the sample introduction. This provides great advantage in simplifying the analysis process. The method is quite easy to use, and there is no need to worry about the source of graphite, that is, the brands or the types of pencil. And the whole process was carried out under atmospheric pressure, offering all the merits that could occur in ambient MS. The improved sensitivity of this method is mainly because of the graphite, which serves as energy-transfer medium to absorb the energy of the photons and release it to the analytes that are adsorbed on the graphite surface. Also, three different laser wavelengths (1064, 532, and 355 nm) was tested to investigate the desorption mechanism. Fifty-one compounds, with varied chemical structures, were tried to prove that this new method possessed universal applicability to detect different kinds of small organic molecules.
语种英语
WOS记录号WOS:000302829800037
出版者AMER CHEMICAL SOC
源URL[http://ir.iccas.ac.cn/handle/121111/49421]  
专题中国科学院化学研究所
通讯作者Liu, Huwei
作者单位Peking Univ, Coll Chem & Mol Engn, Inst Analyt Chem, Beijing Natl Lab Mol Sci,Minist Educ,Key Lab Bioo, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Jialing,Li, Ze,Zhang, Chengsen,et al. Graphite-Coated Paper as Substrate for High Sensitivity Analysis in Ambient Surface-Assisted Laser Desorption/Ionization Mass Spectrometry[J]. ANALYTICAL CHEMISTRY,2012,84(7):3296-3301.
APA Zhang, Jialing.,Li, Ze.,Zhang, Chengsen.,Feng, Baosheng.,Zhou, Zhigui.,...&Liu, Huwei.(2012).Graphite-Coated Paper as Substrate for High Sensitivity Analysis in Ambient Surface-Assisted Laser Desorption/Ionization Mass Spectrometry.ANALYTICAL CHEMISTRY,84(7),3296-3301.
MLA Zhang, Jialing,et al."Graphite-Coated Paper as Substrate for High Sensitivity Analysis in Ambient Surface-Assisted Laser Desorption/Ionization Mass Spectrometry".ANALYTICAL CHEMISTRY 84.7(2012):3296-3301.

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来源:化学研究所

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