Graphite-Coated Paper as Substrate for High Sensitivity Analysis in Ambient Surface-Assisted Laser Desorption/Ionization Mass Spectrometry
文献类型:期刊论文
作者 | Zhang, Jialing; Li, Ze; Zhang, Chengsen; Feng, Baosheng; Zhou, Zhigui; Bai, Yu; Liu, Huwei |
刊名 | ANALYTICAL CHEMISTRY
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出版日期 | 2012-04-03 |
卷号 | 84期号:7页码:3296-3301 |
ISSN号 | 0003-2700 |
DOI | 10.1021/ac300002g |
英文摘要 | In this work, an extremely simple and quite sensitive mass spectrometric method termed ambient surface-assisted laser desorption/ionization mass spectrometry (ambient SALDI-MS) was developed to analyze different kinds of compounds, just using a piece of graphite-coated paper for the sample introduction. This provides great advantage in simplifying the analysis process. The method is quite easy to use, and there is no need to worry about the source of graphite, that is, the brands or the types of pencil. And the whole process was carried out under atmospheric pressure, offering all the merits that could occur in ambient MS. The improved sensitivity of this method is mainly because of the graphite, which serves as energy-transfer medium to absorb the energy of the photons and release it to the analytes that are adsorbed on the graphite surface. Also, three different laser wavelengths (1064, 532, and 355 nm) was tested to investigate the desorption mechanism. Fifty-one compounds, with varied chemical structures, were tried to prove that this new method possessed universal applicability to detect different kinds of small organic molecules. |
语种 | 英语 |
WOS记录号 | WOS:000302829800037 |
出版者 | AMER CHEMICAL SOC |
源URL | [http://ir.iccas.ac.cn/handle/121111/49421] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Liu, Huwei |
作者单位 | Peking Univ, Coll Chem & Mol Engn, Inst Analyt Chem, Beijing Natl Lab Mol Sci,Minist Educ,Key Lab Bioo, Beijing 100871, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Jialing,Li, Ze,Zhang, Chengsen,et al. Graphite-Coated Paper as Substrate for High Sensitivity Analysis in Ambient Surface-Assisted Laser Desorption/Ionization Mass Spectrometry[J]. ANALYTICAL CHEMISTRY,2012,84(7):3296-3301. |
APA | Zhang, Jialing.,Li, Ze.,Zhang, Chengsen.,Feng, Baosheng.,Zhou, Zhigui.,...&Liu, Huwei.(2012).Graphite-Coated Paper as Substrate for High Sensitivity Analysis in Ambient Surface-Assisted Laser Desorption/Ionization Mass Spectrometry.ANALYTICAL CHEMISTRY,84(7),3296-3301. |
MLA | Zhang, Jialing,et al."Graphite-Coated Paper as Substrate for High Sensitivity Analysis in Ambient Surface-Assisted Laser Desorption/Ionization Mass Spectrometry".ANALYTICAL CHEMISTRY 84.7(2012):3296-3301. |
入库方式: OAI收割
来源:化学研究所
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