Screen Anti-influenza Lead Compounds That Target the PA(C) Subunit of H5N1 Viral RNA Polymerase
文献类型：期刊论文
| 作者 | Li, Lin1,3; Chang, Shenghai2,3; Xiang, Junfeng1; Li, Qian1,3; Liang, Huanhuan2; Tang, Yalin1; Liu, Yingfang2 |
| 刊名 | PLOS ONE
 |
| 出版日期 | 2012-08-24 |
| 卷号 | 7期号:8 |
| ISSN号 | 1932-6203 |
| DOI | 10.1371/journal.pone.0035234 |
| 英文摘要 | The avian influenza (H5N1) viral RNA polymerase protein PA(C) was used as a target to screen nine chlorogenic acid derivatives for their polymerase inhibitor activity. Among them, seven compounds were PAC ligands, and four inhibited influenza RNA polymerase activity. These results aid in the design of anti-influenza agents based on caffeoylquinic acid. |
| 语种 | 英语 |
| WOS记录号 | WOS:000308225500001 |
| 出版者 | PUBLIC LIBRARY SCIENCE |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/49769]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Li, Lin |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, State Key Lab Struct Chem Unstable & Stable Speci, BNLMS,Ctr Mol Sci, Beijing 100080, Peoples R China 2.Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, Beijing 100080, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Lin,Chang, Shenghai,Xiang, Junfeng,et al. Screen Anti-influenza Lead Compounds That Target the PA(C) Subunit of H5N1 Viral RNA Polymerase[J]. PLOS ONE,2012,7(8). |
| APA | Li, Lin.,Chang, Shenghai.,Xiang, Junfeng.,Li, Qian.,Liang, Huanhuan.,...&Liu, Yingfang.(2012).Screen Anti-influenza Lead Compounds That Target the PA(C) Subunit of H5N1 Viral RNA Polymerase.PLOS ONE,7(8). |
| MLA | Li, Lin,et al."Screen Anti-influenza Lead Compounds That Target the PA(C) Subunit of H5N1 Viral RNA Polymerase".PLOS ONE 7.8(2012). |
入库方式： OAI收割
来源：化学研究所
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