Visual Detection of DNA Mutation Using Multicolor Fluorescent Coding
文献类型：期刊论文
| 作者 | Song, Jinzhao; Yang, Qiong; Lv, Fengting; Liu, Libing; Wang, Shu |
| 刊名 | ACS APPLIED MATERIALS & INTERFACES
 |
| 出版日期 | 2012-06-01 |
| 卷号 | 4期号:6页码:2885-2890 |
| 关键词 | Conjugated Polymers Fret Dna Mutations Sensors Multicolor Fluorescent Coding |
| ISSN号 | 1944-8244 |
| DOI | 10.1021/am300830r |
| 英文摘要 | A visual colorimetric method for detecting multiplex DNA mutations has been developed using multicolor fluorescent coding based on multistep FRET of cationic conjugated polymers. Expensive instruments and technical expertise are not required in this method. Also our visual system provides a quantitative detection by simply analyzing RGB values of images. Genomic DNAs extracted from 60 FFPE colon tissues can be sensitively determined by utilizing our visual assay with a high-throughput manner. Thus, it proves to be sensitive, reliable, cost-effective, simple, and high-throughput for mutation detection. |
| 语种 | 英语 |
| WOS记录号 | WOS:000305716900011 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/49771]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Yang, Qiong |
| 作者单位 | Chinese Acad Sci, Beijing Natl Lab Mol Sci, Key Lab Organ Solids, Inst Chem, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Song, Jinzhao,Yang, Qiong,Lv, Fengting,et al. Visual Detection of DNA Mutation Using Multicolor Fluorescent Coding[J]. ACS APPLIED MATERIALS & INTERFACES,2012,4(6):2885-2890. |
| APA | Song, Jinzhao,Yang, Qiong,Lv, Fengting,Liu, Libing,&Wang, Shu.(2012).Visual Detection of DNA Mutation Using Multicolor Fluorescent Coding.ACS APPLIED MATERIALS & INTERFACES,4(6),2885-2890. |
| MLA | Song, Jinzhao,et al."Visual Detection of DNA Mutation Using Multicolor Fluorescent Coding".ACS APPLIED MATERIALS & INTERFACES 4.6(2012):2885-2890. |
入库方式： OAI收割
来源：化学研究所
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