DNA Hydrogel by Multicomponent Assembly for Encapsulation and Killing of Cells
文献类型：期刊论文
| 作者 | Hu, Rong; Yuan, Huanxiang; Wang, Bing; Liu, Libing; Lv, Fengting; Wang, Shu |
| 刊名 | ACS APPLIED MATERIALS & INTERFACES
 |
| 出版日期 | 2014-08-13 |
| 卷号 | 6期号:15页码:11823-11828 |
| 关键词 | Dna Cationic Conjugated Polymers Self-assembly Therapeutic Hydrogel Cell Encapsulation |
| ISSN号 | 1944-8244 |
| DOI | 10.1021/am502196h |
| 英文摘要 | In this work, a new multifunctional assembled hydrogel was prepared by incorporating gadolinium ions (Gd3+) with salmon-sperm DNA and polythiophene derivative (PT-COOH) through chelation interactions. Efficient energy transfer from PT-COOH to Gd3+ ions takes place followed by sensitization of oxygen molecule to generate reactive oxygen species (ROS) under light irradiation. Cancer cells can be encapsulated into the hydrogel in situ as the formation of hydrogel followed by killing by the ROS. Integration of imaging modality with therapeutic function within a single assembled hydrogel is therefore anticipated to be a new and challenging design element for new hydrogel materials. |
| 语种 | 英语 |
| WOS记录号 | WOS:000340446300003 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/49971]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Liu, Libing |
| 作者单位 | Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hu, Rong,Yuan, Huanxiang,Wang, Bing,et al. DNA Hydrogel by Multicomponent Assembly for Encapsulation and Killing of Cells[J]. ACS APPLIED MATERIALS & INTERFACES,2014,6(15):11823-11828. |
| APA | Hu, Rong,Yuan, Huanxiang,Wang, Bing,Liu, Libing,Lv, Fengting,&Wang, Shu.(2014).DNA Hydrogel by Multicomponent Assembly for Encapsulation and Killing of Cells.ACS APPLIED MATERIALS & INTERFACES,6(15),11823-11828. |
| MLA | Hu, Rong,et al."DNA Hydrogel by Multicomponent Assembly for Encapsulation and Killing of Cells".ACS APPLIED MATERIALS & INTERFACES 6.15(2014):11823-11828. |
入库方式： OAI收割
来源：化学研究所
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