A label-free double-amplification system for sensitive detection of single-stranded DNA and thrombin by liquid chromatography-mass spectrometry
文献类型：期刊论文
| 作者 | Zhao, Wenbo; Qin, Zhen; Zhang, Chengsen; Zhao, Meiping; Luo, Hai |
| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2014-09-07 |
| 卷号 | 50期号:69页码:9846-9848 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/c4cc03559c |
| 英文摘要 | A label-free double amplification system has been developed by using a ternary DNA probe containing the poly(adenine-thymine) sequence assisted by exonuclease III degradation. The method achieved more than 600-fold signal amplification and allowed sensitive detection of single-stranded DNA and thrombin at the pM level by using liquid chromatography/mass spectrometry. |
| 语种 | 英语 |
| 出版者 | ROYAL SOC CHEMISTRY |
| WOS记录号 | WOS:000340513400008 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/50063]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Zhao, Meiping |
| 作者单位 | Peking Univ, Coll Chem & Mol Engn, MOE Key Lab Bioorgan Chem & Mol Engn, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Wenbo,Qin, Zhen,Zhang, Chengsen,et al. A label-free double-amplification system for sensitive detection of single-stranded DNA and thrombin by liquid chromatography-mass spectrometry[J]. CHEMICAL COMMUNICATIONS,2014,50(69):9846-9848. |
| APA | Zhao, Wenbo,Qin, Zhen,Zhang, Chengsen,Zhao, Meiping,&Luo, Hai.(2014).A label-free double-amplification system for sensitive detection of single-stranded DNA and thrombin by liquid chromatography-mass spectrometry.CHEMICAL COMMUNICATIONS,50(69),9846-9848. |
| MLA | Zhao, Wenbo,et al."A label-free double-amplification system for sensitive detection of single-stranded DNA and thrombin by liquid chromatography-mass spectrometry".CHEMICAL COMMUNICATIONS 50.69(2014):9846-9848. |
入库方式： OAI收割
来源：化学研究所
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