Salt Effect in High-voltage Assisted Laser Desorption Ionization Mass Spectrometry
文献类型:期刊论文
作者 | Ren Xin-Xin; Qiu Ran; Luo Hai |
刊名 | CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
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出版日期 | 2014-11-01 |
卷号 | 42期号:11页码:1697-1701 |
关键词 | High-voltage Assisted Laser Desorption Ionization Mass Spectrometry Salt Effect Signal Enhancement Beta-cyclodextrin Complex |
ISSN号 | 0253-3820 |
英文摘要 | Salt effect in high-voltage assisted laser desorption ionization mass spectrometry (HALDI-MS) has been studied under both positive and negative ion modes using L-tyrosine, beta-cyclodextrin, alpha-lipoic acid, as well as the complex formed between alpha-lipoic acid and beta-cyclodextrin as the test analytes. Compared the mass spectra obtained with and without the addition of salt, it is found that HALDI-MS can tolerate a higher amount of salt than electro spray ionization mass spectrometry (ESI-MS). Also, the addition of salt can enhance the HALDI-MS signal intensity of the complex ion of alpha-lipoic acid and beta-cyclodextrin, and we suggest that such signal-enhancement effect is due to the formation of the three component complex consisting of alpha-lipoic acid, beta-cyclodextrin and the positive ion of the salt. |
语种 | 英语 |
WOS记录号 | WOS:000346762000017 |
出版者 | ELSEVIER SCIENCE INC |
源URL | [http://ir.iccas.ac.cn/handle/121111/50323] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Luo Hai |
作者单位 | Peking Univ, Coll Chem & Mol Engn, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China |
推荐引用方式 GB/T 7714 | Ren Xin-Xin,Qiu Ran,Luo Hai. Salt Effect in High-voltage Assisted Laser Desorption Ionization Mass Spectrometry[J]. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,2014,42(11):1697-1701. |
APA | Ren Xin-Xin,Qiu Ran,&Luo Hai.(2014).Salt Effect in High-voltage Assisted Laser Desorption Ionization Mass Spectrometry.CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,42(11),1697-1701. |
MLA | Ren Xin-Xin,et al."Salt Effect in High-voltage Assisted Laser Desorption Ionization Mass Spectrometry".CHINESE JOURNAL OF ANALYTICAL CHEMISTRY 42.11(2014):1697-1701. |
入库方式: OAI收割
来源:化学研究所
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