Aggregation-induced emission dye based luminescent silica nanoparticles: facile preparation, biocompatibility evaluation and cell imaging applications
文献类型：期刊论文
| 作者 | Zhang, Xiaoyong1,2,3; Zhang, Xiqi2,3; Yang, Bin2,3; Liu, Liangji4; Hui, Junfeng2,3; Liu, Meiying5; Chen, Yiwang1; Wei, Yen2,3 |
| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2014 |
| 卷号 | 4期号:20页码:10060-10066 |
| ISSN号 | 2046-2069 |
| DOI | 10.1039/c3ra46076b |
| 英文摘要 | In this work, we reported for the first time that luminescent silica nanoparticles could be easily fabricated by the encapsulation of an aggregation-induced emission dye (named An18) via a modified Stober method. In this method, octadecyltrimethoxysilane (C18-Si) and An18 were first self assembled and served as the core of the silica nanoparticles. Then another silicate precursor, tetraethoxysilane, was further coated on the luminescent core, thus forming luminescent silica nanoparticles. The properties of the thus obtained luminescent silica nanoparticles (named An18-SiO2 NPs) were investigated by fluorescence spectroscopy, transmission electron microscopy and Fourier transform infrared spectroscopy. The biocompatibility and cell uptake behavior of the An18-SiO2 NPs were further investigated to evaluate their potential for biomedical applications. Our results demonstrated that the An18-SiO2 NPs have a uniform spherical morphology (with diameter of 70-80 nm), high water dispersibility, remarkable fluorescent properties and excellent biocompatibility, making them a promising candidate material for various biomedical applications. |
| 语种 | 英语 |
| WOS记录号 | WOS:000332061300024 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/50589]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Zhang, Xiaoyong |
| 作者单位 | 1.Nanchang Univ, Inst Polymers, Dept Chem, Nanchang 330031, Peoples R China 2.Tsinghua Univ, Minist Educ, Dept Chem, Beijing 100084, Peoples R China 3.Tsinghua Univ, Minist Educ, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Beijing 100084, Peoples R China 4.Jiangxi Univ Tradit Chinese Med, Affiliated Hosp, Nanchang, Peoples R China 5.Chinese Acad Sci, Inst Chem, New Mat Lab, Beijing Natl Lab Mol Sci,Key Lab Organ Solids, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Xiaoyong,Zhang, Xiqi,Yang, Bin,et al. Aggregation-induced emission dye based luminescent silica nanoparticles: facile preparation, biocompatibility evaluation and cell imaging applications[J]. RSC ADVANCES,2014,4(20):10060-10066. |
| APA | Zhang, Xiaoyong.,Zhang, Xiqi.,Yang, Bin.,Liu, Liangji.,Hui, Junfeng.,...&Wei, Yen.(2014).Aggregation-induced emission dye based luminescent silica nanoparticles: facile preparation, biocompatibility evaluation and cell imaging applications.RSC ADVANCES,4(20),10060-10066. |
| MLA | Zhang, Xiaoyong,et al."Aggregation-induced emission dye based luminescent silica nanoparticles: facile preparation, biocompatibility evaluation and cell imaging applications".RSC ADVANCES 4.20(2014):10060-10066. |
入库方式： OAI收割
来源：化学研究所
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