Design and Fabrication of a Biomimetic Nanochannel for Highly Sensitive Arginine Response in Serum Samples
文献类型:期刊论文
作者 | Song, Miaomiao1; Sun, Zhongyue1; Han, Cuiping1; Tian, Demei1; Li, Haibing1; Jiang, Lei2 |
刊名 | CHEMISTRY-A EUROPEAN JOURNAL
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出版日期 | 2014-06-23 |
卷号 | 20期号:26页码:7987-7993 |
关键词 | Arginine Calixarene Click Chemistry Nanochannel Sensor |
ISSN号 | 0947-6539 |
DOI | 10.1002/chem.201400138 |
英文摘要 | Inspired from their biological counterparts, chemical modification of the interior surface of nanochannels with functional molecules may provide a highly efficient means to control ionic or molecular transport through nanochannels. Herein, we have designed and prepared a aldehyde calix[4] arene (C4AH), which was attached to the interior surface of a single nanochannel by using a click reaction, and that showed a high response for arginine (Arg). Furthermore, the nanofluidic sensing system has been challenged with complex matrices containing a high concentration of interfering sequences and serum. Based on this finding, we believe that the artificial nanochannel can be used for practical Arg-sensing devices, and be applied in a biological environment. |
语种 | 英语 |
WOS记录号 | WOS:000337742600019 |
出版者 | WILEY-V C H VERLAG GMBH |
源URL | [http://ir.iccas.ac.cn/handle/121111/50661] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Li, Haibing |
作者单位 | 1.Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Peoples R China 2.Chinese Acad Sci, Key Lab Organ Solids, Inst Chem, Beijing Natl Lab Mol Sci BNLMS, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Song, Miaomiao,Sun, Zhongyue,Han, Cuiping,et al. Design and Fabrication of a Biomimetic Nanochannel for Highly Sensitive Arginine Response in Serum Samples[J]. CHEMISTRY-A EUROPEAN JOURNAL,2014,20(26):7987-7993. |
APA | Song, Miaomiao,Sun, Zhongyue,Han, Cuiping,Tian, Demei,Li, Haibing,&Jiang, Lei.(2014).Design and Fabrication of a Biomimetic Nanochannel for Highly Sensitive Arginine Response in Serum Samples.CHEMISTRY-A EUROPEAN JOURNAL,20(26),7987-7993. |
MLA | Song, Miaomiao,et al."Design and Fabrication of a Biomimetic Nanochannel for Highly Sensitive Arginine Response in Serum Samples".CHEMISTRY-A EUROPEAN JOURNAL 20.26(2014):7987-7993. |
入库方式: OAI收割
来源:化学研究所
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