A DNA-templated synthesis of encoded small molecules by DNA self-assembly
文献类型:期刊论文
作者 | Cao, Cheng1; Zhao, Peng1; Li, Ze1; Chen, Zitian3,4; Huang, Yanyi3,4; Bai, Yu1; Li, Xiaoyu1,2 |
刊名 | CHEMICAL COMMUNICATIONS |
出版日期 | 2014 |
卷号 | 50期号:75页码:10997-10999 |
ISSN号 | 1359-7345 |
DOI | 10.1039/c4cc03380a |
英文摘要 | We report a novel method for the synthesis of DNA-encoded libraries without the need for discrete DNA template. Reactant DNAs self-assemble to enable chemical reactions and photo-cleavage transfers the product to the DNA terminus, making it suitable for the subsequent affinity-based selection and hit deconvolution. |
语种 | 英语 |
出版者 | ROYAL SOC CHEMISTRY |
WOS记录号 | WOS:000340900400019 |
源URL | [http://ir.iccas.ac.cn/handle/121111/50909] |
专题 | 中国科学院化学研究所 |
通讯作者 | Bai, Yu |
作者单位 | 1.Peking Univ, Coll Chem & Mol Engn, BNLMS, Key Lab Bioorgan Chem & Mol Engn,Minist Educ, Beijing 100871, Peoples R China 2.Peking Univ, Shenzhen Grad Sch, Sch Chem Biol & Biotechnol, Key Lab Chem Genom, Shenzhen 518055, Peoples R China 3.Peking Univ, Biodynam Opt Imaging Ctr BIOPIC, Beijing 100871, Peoples R China 4.Peking Univ, Coll Engn, Beijing 100871, Peoples R China |
推荐引用方式 GB/T 7714 | Cao, Cheng,Zhao, Peng,Li, Ze,et al. A DNA-templated synthesis of encoded small molecules by DNA self-assembly[J]. CHEMICAL COMMUNICATIONS,2014,50(75):10997-10999. |
APA | Cao, Cheng.,Zhao, Peng.,Li, Ze.,Chen, Zitian.,Huang, Yanyi.,...&Li, Xiaoyu.(2014).A DNA-templated synthesis of encoded small molecules by DNA self-assembly.CHEMICAL COMMUNICATIONS,50(75),10997-10999. |
MLA | Cao, Cheng,et al."A DNA-templated synthesis of encoded small molecules by DNA self-assembly".CHEMICAL COMMUNICATIONS 50.75(2014):10997-10999. |
入库方式: OAI收割
来源:化学研究所
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