Carbon Nanoparticles Trapped in Vivo-Similar to Carbon Nanotubes in Time-Dependent Biodistribution
文献类型：期刊论文
| 作者 | Liu, Jia-Hui1,2; Yang, Sheng-Tao3; Wang, Xin4,5; Wang, Haifang1; Liu, Yamin4,5; Luo, Pengju G.4,5; Liu, Yuanfang1,6; Sun, Ya-Ping4,5 |
| 刊名 | ACS APPLIED MATERIALS & INTERFACES
 |
| 出版日期 | 2014-08-27 |
| 卷号 | 6期号:16页码:14672-14678 |
| 关键词 | Carbon Nanoparticles Biodistribution Carbon Nanotubes Toxicity C-13 Labeling Isotope-ratio Mass Spectroscopy |
| ISSN号 | 1944-8244 |
| DOI | 10.1021/am504022s |
| 英文摘要 | Carbon nanoparticles are in all of the carbon nanomaterials that are presently widely pursued for potential bioapplications, but their in vivo biodistribution-related properties are largely unknown. In this work, highly C-13-enriched carbon nanopartides were prepared to allow their quantification in biological samples by using isotope-ratio mass spectroscopy. The in vivo biodistribution results are presented and discussed, and also compared with those of the aqueous suspended carbon nanotubes reported previously. The distribution profile and time dependencies are largely similar between the nanoparticles and nanotubes, with results on both suggesting meaningful accumulation in some major organs over an extended period of time. Therefore, the surface modification of carbon nanoparticles, preferably the chemical functionalization of the nanoparticles with biocompatible molecules or species, is desirable or necessary in the pursuit of these nanomaterials for various bioapplications. |
| 语种 | 英语 |
| WOS记录号 | WOS:000341122000162 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/51001]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Yang, Sheng-Tao |
| 作者单位 | 1.Shanghai Univ, Inst Nanochem & Nanobiol, Shanghai 200444, Peoples R China 2.Beijing Univ Chem Technol, Beijing Key Lab Bioproc, Coll Life Sci & Technol, Beijing 100029, Peoples R China 3.Southwest Univ Nationalities, Coll Chem & Environm Protect Engn, Chengdu 610041, Peoples R China 4.Clemson Univ, Dept Chem, Clemson, SC 29634 USA 5.Clemson Univ, Lab Emerging Mat & Technol, Clemson, SC 29634 USA 6.Peking Univ, Beijing Natl Lab Mol Sci, Coll Chem & Mol Engn, Beijing 100871, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Jia-Hui,Yang, Sheng-Tao,Wang, Xin,et al. Carbon Nanoparticles Trapped in Vivo-Similar to Carbon Nanotubes in Time-Dependent Biodistribution[J]. ACS APPLIED MATERIALS & INTERFACES,2014,6(16):14672-14678. |
| APA | Liu, Jia-Hui.,Yang, Sheng-Tao.,Wang, Xin.,Wang, Haifang.,Liu, Yamin.,...&Sun, Ya-Ping.(2014).Carbon Nanoparticles Trapped in Vivo-Similar to Carbon Nanotubes in Time-Dependent Biodistribution.ACS APPLIED MATERIALS & INTERFACES,6(16),14672-14678. |
| MLA | Liu, Jia-Hui,et al."Carbon Nanoparticles Trapped in Vivo-Similar to Carbon Nanotubes in Time-Dependent Biodistribution".ACS APPLIED MATERIALS & INTERFACES 6.16(2014):14672-14678. |
入库方式： OAI收割
来源：化学研究所
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