Surface modification of poly (styrene-b-(ethylene-co-butylene)-b-styrene) elastomer and its plasma protein adsorption by QCM-D
文献类型：期刊论文
| 作者 | Li, Rui1; Jin, Jing2; Sun, Yingchun1 |
| 刊名 | APPLIED SURFACE SCIENCE
 |
| 出版日期 | 2014-05-15 |
| 卷号 | 301页码:300-306 |
| 关键词 | Poly (Styrene-b-(Ethylene-co-butylene)-b-styrene) (Sebs) Copolymer Poly (Ethylene Glycol) (Peg) Qcm-d Hemocompatibility Protein Adsorption |
| ISSN号 | 0169-4332 |
| DOI | 10.1016/j.apsusc.2014.02.068 |
| 英文摘要 | Protein adsorption is a dynamic process and plays a major role in determining the hemocompatibility of biomaterials. We have obtained different poly (ethylene glycol) (PEG) graft concentrations of SEBS-g-PEG and the surface chemical compositions are confirmed by X-ray photoelectron spectroscopy (XPS). Graft concentration is defined by peak-area ratio of [C-O]/[C] on modified SEBS surface. With increasing graft concentration, water contact angles of the modified SEBS have significantly decreased. The platelet adhesion and static protein adsorption demonstrate that the hemocompatibility of copolymers films are improved effectively and SEBS-g-PEG-2 with larger graft concentration has more superior anticoagulation than that of SEBS-g-PEG-1. Moreover, we have quantitatively investigated the adsorption process of bovine serum albumin (BSA) and fibrinogen (Fib) on the surfaces of pristine SEBS and modified SEBS using quartz crystal microbalance with dissipation (QCM-D) in real time. The results indicate that the inactivated BSA on the pristine SEBS can continuously induce the subsequent Fib adsorption. The hemocompatibility of SEBS-g-PEG-2 with the graft concentration of 0.207 has excellent anti-protein property and the bio-inert BSA layer on the film can resist the subsequent Fib adsorption. Crown Copyright (C) 2014 Published by Elsevier B.V. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000335095600045 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/51251]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Jin, Jing |
| 作者单位 | 1.NE Normal Univ, Sch Phys, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Rui,Jin, Jing,Sun, Yingchun. Surface modification of poly (styrene-b-(ethylene-co-butylene)-b-styrene) elastomer and its plasma protein adsorption by QCM-D[J]. APPLIED SURFACE SCIENCE,2014,301:300-306. |
| APA | Li, Rui,Jin, Jing,&Sun, Yingchun.(2014).Surface modification of poly (styrene-b-(ethylene-co-butylene)-b-styrene) elastomer and its plasma protein adsorption by QCM-D.APPLIED SURFACE SCIENCE,301,300-306. |
| MLA | Li, Rui,et al."Surface modification of poly (styrene-b-(ethylene-co-butylene)-b-styrene) elastomer and its plasma protein adsorption by QCM-D".APPLIED SURFACE SCIENCE 301(2014):300-306. |
入库方式： OAI收割
来源：化学研究所
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