In vitro and in vivo antitumor activity of a novel hypocrellin B derivative for photodynamic therapy
文献类型:期刊论文
作者 | Zhao, Hongyou1; Yin, Rong2; Chen, Defu3; Ren, Jie1; Wang, Yucheng4; Zhanga, Jiaying1; Deng, Hong5; Wang, Ying1; Qiu, Haixia1; Huang, Naiyan1 |
刊名 | PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
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出版日期 | 2014-06-01 |
卷号 | 11期号:2页码:204-212 |
关键词 | Pdt Hypocrellin b Derivative Mitochondria Apoptosis In Vivo Pdt Activity |
ISSN号 | 1572-1000 |
DOI | 10.1016/j.pdpdt.2014.01.003 |
英文摘要 | Background: Photodynamic therapy (PDT) is an approved therapeutic procedure that exerts cytotoxic activity toward tumor cells by irradiating photosensitizers with light exposure to produce reactive oxygen species (ROS). An ideal photosensitizer is a crucial element to PDT. In the current study, we evaluated the photodynamic activity of a novel photosensitizer, the derivative of hypocrellin B (HB), 17-(3-amino-1-pentanesulfonic acid)-substituted hypocrellin B Schiff-base (PENSHB), both in vitro and in vivo. |
语种 | 英语 |
WOS记录号 | WOS:000337862500019 |
出版者 | ELSEVIER SCIENCE BV |
源URL | [http://ir.iccas.ac.cn/handle/121111/51455] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Gu, Ying |
作者单位 | 1.Chinese Peoples Liberat Army Gen Hosp, Dept Laser Med, Beijing 100853, Peoples R China 2.Shanxi Med Univ, Hosp 2, Dept Dermatol, Taiyuan 030001, Peoples R China 3.Beijing Inst Technol, Sch Informat & Elect, Beijing 100081, Peoples R China 4.Nankai Univ, Coll Med, Tianjin 300071, Peoples R China 5.Chinese Acad Sci, Inst Chem, Key Lab Photochem, BNLMS, Beijing 100080, Peoples R China 6.Chinese Acad Sci, Tech Inst Phys & Chem, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Zhao, Hongyou,Yin, Rong,Chen, Defu,et al. In vitro and in vivo antitumor activity of a novel hypocrellin B derivative for photodynamic therapy[J]. PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY,2014,11(2):204-212. |
APA | Zhao, Hongyou.,Yin, Rong.,Chen, Defu.,Ren, Jie.,Wang, Yucheng.,...&Gu, Ying.(2014).In vitro and in vivo antitumor activity of a novel hypocrellin B derivative for photodynamic therapy.PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY,11(2),204-212. |
MLA | Zhao, Hongyou,et al."In vitro and in vivo antitumor activity of a novel hypocrellin B derivative for photodynamic therapy".PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY 11.2(2014):204-212. |
入库方式: OAI收割
来源:化学研究所
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