中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
In vitro and in vivo antitumor activity of a novel hypocrellin B derivative for photodynamic therapy

文献类型:期刊论文

作者Zhao, Hongyou1; Yin, Rong2; Chen, Defu3; Ren, Jie1; Wang, Yucheng4; Zhanga, Jiaying1; Deng, Hong5; Wang, Ying1; Qiu, Haixia1; Huang, Naiyan1
刊名PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
出版日期2014-06-01
卷号11期号:2页码:204-212
关键词Pdt Hypocrellin b Derivative Mitochondria Apoptosis In Vivo Pdt Activity
ISSN号1572-1000
DOI10.1016/j.pdpdt.2014.01.003
英文摘要Background: Photodynamic therapy (PDT) is an approved therapeutic procedure that exerts cytotoxic activity toward tumor cells by irradiating photosensitizers with light exposure to produce reactive oxygen species (ROS). An ideal photosensitizer is a crucial element to PDT. In the current study, we evaluated the photodynamic activity of a novel photosensitizer, the derivative of hypocrellin B (HB), 17-(3-amino-1-pentanesulfonic acid)-substituted hypocrellin B Schiff-base (PENSHB), both in vitro and in vivo.
语种英语
WOS记录号WOS:000337862500019
出版者ELSEVIER SCIENCE BV
源URL[http://ir.iccas.ac.cn/handle/121111/51455]  
专题中国科学院化学研究所
通讯作者Gu, Ying
作者单位1.Chinese Peoples Liberat Army Gen Hosp, Dept Laser Med, Beijing 100853, Peoples R China
2.Shanxi Med Univ, Hosp 2, Dept Dermatol, Taiyuan 030001, Peoples R China
3.Beijing Inst Technol, Sch Informat & Elect, Beijing 100081, Peoples R China
4.Nankai Univ, Coll Med, Tianjin 300071, Peoples R China
5.Chinese Acad Sci, Inst Chem, Key Lab Photochem, BNLMS, Beijing 100080, Peoples R China
6.Chinese Acad Sci, Tech Inst Phys & Chem, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714
Zhao, Hongyou,Yin, Rong,Chen, Defu,et al. In vitro and in vivo antitumor activity of a novel hypocrellin B derivative for photodynamic therapy[J]. PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY,2014,11(2):204-212.
APA Zhao, Hongyou.,Yin, Rong.,Chen, Defu.,Ren, Jie.,Wang, Yucheng.,...&Gu, Ying.(2014).In vitro and in vivo antitumor activity of a novel hypocrellin B derivative for photodynamic therapy.PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY,11(2),204-212.
MLA Zhao, Hongyou,et al."In vitro and in vivo antitumor activity of a novel hypocrellin B derivative for photodynamic therapy".PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY 11.2(2014):204-212.

入库方式: OAI收割

来源:化学研究所

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