Supramolecular hydrogels assembled from nonionic poly(ethylene glycol)-b-polypeptide diblocks containing OEGylated poly-L-glutamate
文献类型：期刊论文
| 作者 | Zhang, Shusheng; Fu, Wenxin; Li, Zhibo |
| 刊名 | POLYMER CHEMISTRY
 |
| 出版日期 | 2014 |
| 卷号 | 5期号:10页码:3346-3351 |
| ISSN号 | 1759-9954 |
| DOI | 10.1039/c4py00016a |
| 英文摘要 | A poly(ethylene glycol)-b-poly(g-(2-methoxyethoxy)esteryl-L-glutamate) (PEG-b-poly-L-EG(2)Glu) diblock was prepared by the ring-opening polymerization (ROP) of L-EG(2)Glu N-carboxyanhydride (NCA) using PEG-NH2 as the macroinitiator. When the average degree of polymerization (DP) for poly-L-EG(2)Glu was below 40, the PEG-b-poly-L-EG(2)Glu diblock could spontaneously form hydrogels in water. For the different diblocks, a thermally-induced increase in mechanical strength was observed for the PEG-b-poly-L-EG(2)Glu diblock between 20-45 degrees C. Transmission electron microscopy (TEM) and atomic force microscopy (AFM) revealed that continuous networks of nanoribbons were formed in these hydrogel samples. Circular dichroism (CD) and Fourier transform infrared spectroscopy (FTIR) characterization suggested that the formation of sufficient beta-sheet content accounted for the nanoribbon assemblies and hydrogel networks. The minimal gelation concentration and gel mechanical properties were found to strongly depend on the composition of the PEG-b-poly-L-EG(2)Glu diblocks. |
| 语种 | 英语 |
| 出版者 | ROYAL SOC CHEMISTRY |
| WOS记录号 | WOS:000334833900009 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/51867]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Fu, Wenxin |
| 作者单位 | Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Shusheng,Fu, Wenxin,Li, Zhibo. Supramolecular hydrogels assembled from nonionic poly(ethylene glycol)-b-polypeptide diblocks containing OEGylated poly-L-glutamate[J]. POLYMER CHEMISTRY,2014,5(10):3346-3351. |
| APA | Zhang, Shusheng,Fu, Wenxin,&Li, Zhibo.(2014).Supramolecular hydrogels assembled from nonionic poly(ethylene glycol)-b-polypeptide diblocks containing OEGylated poly-L-glutamate.POLYMER CHEMISTRY,5(10),3346-3351. |
| MLA | Zhang, Shusheng,et al."Supramolecular hydrogels assembled from nonionic poly(ethylene glycol)-b-polypeptide diblocks containing OEGylated poly-L-glutamate".POLYMER CHEMISTRY 5.10(2014):3346-3351. |
入库方式： OAI收割
来源：化学研究所
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