Manganese- Catalyzed Dehydrogenative [4+2] Annulation of N-H Imines and Alkynes by C- H/N- H Activation**
文献类型：期刊论文
| 作者 | He, Ruoyu; Huang, Zhi-Tang; Zheng, Qi-Yu; Wang, Congyang |
| 刊名 | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
 |
| 出版日期 | 2014-05-05 |
| 卷号 | 53期号:19页码:4950-4953 |
| 关键词 | Alkynes Ch Activation Heterocycles Manganese Synthetic Methods |
| ISSN号 | 1433-7851 |
| DOI | 10.1002/anie.201402575 |
| 英文摘要 | Described herein is a manganese-catalyzed dehydrogenative [4+2] annulation of NH imines and alkynes, a reaction providing highly atom-economical access to diverse isoquinolines. This transformation represents the first example of manganese-catalyzed CH activation of imines; the stoichiometric variant of the cyclomanganation was reported in 1971. The redox neutral reaction produces H-2 as the major byproduct and eliminates the need for any oxidants, external ligands, or additives, thus standing out from known isoquinoline synthesis by transition-metal-catalyzed CH activation. Mechanistic studies revealed the five-membered manganacycle and manganese hydride species as key reaction intermediates in the catalytic cycle. |
| 语种 | 英语 |
| WOS记录号 | WOS:000335202700035 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/52385]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wang, Congyang |
| 作者单位 | Chinese Acad Sci, Beijing Natl Lab Mol Sci, CAS Key Lab Mol Recognit & Funct, Inst Chem, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | He, Ruoyu,Huang, Zhi-Tang,Zheng, Qi-Yu,et al. Manganese- Catalyzed Dehydrogenative [4+2] Annulation of N-H Imines and Alkynes by C- H/N- H Activation**[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2014,53(19):4950-4953. |
| APA | He, Ruoyu,Huang, Zhi-Tang,Zheng, Qi-Yu,&Wang, Congyang.(2014).Manganese- Catalyzed Dehydrogenative [4+2] Annulation of N-H Imines and Alkynes by C- H/N- H Activation**.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,53(19),4950-4953. |
| MLA | He, Ruoyu,et al."Manganese- Catalyzed Dehydrogenative [4+2] Annulation of N-H Imines and Alkynes by C- H/N- H Activation**".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 53.19(2014):4950-4953. |
入库方式： OAI收割
来源：化学研究所
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