中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Collective Synthesis of Cladiellins Based on the Gold-Catalyzed Cascade Reaction of 1,7-Diynes

文献类型:期刊论文

作者Yue, Guozong3; Zhang, Yun3; Fang, Lichao3; Li, Chuang-chuang3; Luo, Tuoping1,2; Yang, Zhen1,2,3
刊名ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
出版日期2014-02-10
卷号53期号:7页码:1837-1840
关键词Cascade Reaction Cyclization Gold Natural Products Total Synthesis
ISSN号1433-7851
DOI10.1002/anie.201309449
英文摘要The cladiellin family of natural products, which includes molecules with various biological activities, continues to invite new synthetic studies. A gold-catalyzed tandem reaction of 1,7-diynes to construct the 6-5-bicyclic ring systems that are present in a number of natural products was developed. This reaction was applied as the key step to realize the formal and total syntheses of nine members of the cladiellin family in an enantio- and diastereoselective manner. This modular and efficient approach could also be used for the construction of other cladiellins, as well as their analogues, for follow-up studies.
语种英语
WOS记录号WOS:000330680400014
出版者WILEY-V C H VERLAG GMBH
源URL[http://ir.iccas.ac.cn/handle/121111/52607]  
专题中国科学院化学研究所
通讯作者Luo, Tuoping
作者单位1.Peking Univ, Key Lab Bioorgan Chem & Mol Engn, Minist Educ, Beijing 100871, Peoples R China
2.Peking Univ, Peking Tsinghua Ctr Life Sci, BNLMS, Beijing 100871, Peoples R China
3.Peking Univ, Shenzhen Grad Sch, Lab Chem Genom, Sch Chem Biol & Biotechnol, Shenzhen 518055, Peoples R China
推荐引用方式
GB/T 7714
Yue, Guozong,Zhang, Yun,Fang, Lichao,et al. Collective Synthesis of Cladiellins Based on the Gold-Catalyzed Cascade Reaction of 1,7-Diynes[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2014,53(7):1837-1840.
APA Yue, Guozong,Zhang, Yun,Fang, Lichao,Li, Chuang-chuang,Luo, Tuoping,&Yang, Zhen.(2014).Collective Synthesis of Cladiellins Based on the Gold-Catalyzed Cascade Reaction of 1,7-Diynes.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,53(7),1837-1840.
MLA Yue, Guozong,et al."Collective Synthesis of Cladiellins Based on the Gold-Catalyzed Cascade Reaction of 1,7-Diynes".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 53.7(2014):1837-1840.

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来源:化学研究所

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