Collective Synthesis of Cladiellins Based on the Gold-Catalyzed Cascade Reaction of 1,7-Diynes
文献类型:期刊论文
作者 | Yue, Guozong3; Zhang, Yun3; Fang, Lichao3; Li, Chuang-chuang3; Luo, Tuoping1,2; Yang, Zhen1,2,3 |
刊名 | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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出版日期 | 2014-02-10 |
卷号 | 53期号:7页码:1837-1840 |
关键词 | Cascade Reaction Cyclization Gold Natural Products Total Synthesis |
ISSN号 | 1433-7851 |
DOI | 10.1002/anie.201309449 |
英文摘要 | The cladiellin family of natural products, which includes molecules with various biological activities, continues to invite new synthetic studies. A gold-catalyzed tandem reaction of 1,7-diynes to construct the 6-5-bicyclic ring systems that are present in a number of natural products was developed. This reaction was applied as the key step to realize the formal and total syntheses of nine members of the cladiellin family in an enantio- and diastereoselective manner. This modular and efficient approach could also be used for the construction of other cladiellins, as well as their analogues, for follow-up studies. |
语种 | 英语 |
WOS记录号 | WOS:000330680400014 |
出版者 | WILEY-V C H VERLAG GMBH |
源URL | [http://ir.iccas.ac.cn/handle/121111/52607] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Luo, Tuoping |
作者单位 | 1.Peking Univ, Key Lab Bioorgan Chem & Mol Engn, Minist Educ, Beijing 100871, Peoples R China 2.Peking Univ, Peking Tsinghua Ctr Life Sci, BNLMS, Beijing 100871, Peoples R China 3.Peking Univ, Shenzhen Grad Sch, Lab Chem Genom, Sch Chem Biol & Biotechnol, Shenzhen 518055, Peoples R China |
推荐引用方式 GB/T 7714 | Yue, Guozong,Zhang, Yun,Fang, Lichao,et al. Collective Synthesis of Cladiellins Based on the Gold-Catalyzed Cascade Reaction of 1,7-Diynes[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2014,53(7):1837-1840. |
APA | Yue, Guozong,Zhang, Yun,Fang, Lichao,Li, Chuang-chuang,Luo, Tuoping,&Yang, Zhen.(2014).Collective Synthesis of Cladiellins Based on the Gold-Catalyzed Cascade Reaction of 1,7-Diynes.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,53(7),1837-1840. |
MLA | Yue, Guozong,et al."Collective Synthesis of Cladiellins Based on the Gold-Catalyzed Cascade Reaction of 1,7-Diynes".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 53.7(2014):1837-1840. |
入库方式: OAI收割
来源:化学研究所
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