Red emissive cross-linked chitosan and their nanoparticles for imaging the nucleoli of living cells
文献类型：期刊论文
| 作者 | Wang, Ke1; Yuan, Xun1; Guo, Zhenpeng1,2; Xu, Hying1,2; Chen, Yi1,2 |
| 刊名 | CARBOHYDRATE POLYMERS
 |
| 出版日期 | 2014-02-15 |
| 卷号 | 102页码:699-707 |
| 关键词 | Preparation Chitosan Red Luminescence Nanoparticles Imaging |
| ISSN号 | 0144-8617 |
| DOI | 10.1016/j.carbpol.2013.10.100 |
| 英文摘要 | Biocompatible glutaraldehyde-cross-linked chitosan with new red fluorescence were prepared for the first time and were shaped into nanoparticles via inverse-microemulsion method. They could luminesce at ca. 670 nm either as powders and nanoparticles or in real and gelling solutions or suspensions, having a lifetime of 1.353 ns and a quantum yield of 0.08 in solution or 0.01 in solid state. The new-formed pyridinium structures and the intramolecular charge transfer effect are considered to be responsible for the new red emission, which have been proved by FTIR, 13C NMR, and some calculation using Gaussian 09, respectively. Strikingly, they are quite inert and anti-photobleaching, with only <3% loss of fluorescent intensity per minute in average under a continuous laser illumination at 633 nm and 50 Especially, their nanoparticles (5.6 nm) could enter into the negative nucleoli of living HeLa cells with low cytotoxicity for high contrast imaging inspections. (C) 2013 Elsevier Ltd. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000331779600092 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/52921]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Chen, Yi |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Key Lab Analyt Chem Living Biosyst, Beijing 100190, Peoples R China 2.Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Ke,Yuan, Xun,Guo, Zhenpeng,et al. Red emissive cross-linked chitosan and their nanoparticles for imaging the nucleoli of living cells[J]. CARBOHYDRATE POLYMERS,2014,102:699-707. |
| APA | Wang, Ke,Yuan, Xun,Guo, Zhenpeng,Xu, Hying,&Chen, Yi.(2014).Red emissive cross-linked chitosan and their nanoparticles for imaging the nucleoli of living cells.CARBOHYDRATE POLYMERS,102,699-707. |
| MLA | Wang, Ke,et al."Red emissive cross-linked chitosan and their nanoparticles for imaging the nucleoli of living cells".CARBOHYDRATE POLYMERS 102(2014):699-707. |
入库方式： OAI收割
来源：化学研究所
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